Contact HealthDay
Tel: 203.855.1400 or E-mail

News By Specialty

Allergy
Anesthesiology
Cardiology
Cosmetic Surgery
Critical Care
Dermatology
Diabetes & Endocrinology
Emergency Medicine
Family Practice
Gastroenterology
Geriatrics
Hematology & Oncology
HIV & AIDS
Infectious Disease
Internal Medicine
Nephrology
Neurology
Nursing
OBGYN & Women's Health
Ophthalmology
Orthopedics
Otolaryngology
Pain Management
Pathology
Pediatrics
Pharmacy
Psychiatry
Pulmonology
Radiology
Rheumatology
Surgery
Urology

Follow us on:

    


e-Healthcare Leadership Awards


Metformin Usually Adequate for Control of Gestational Diabetes
About 26 percent of women initially treated with metformin require supplemental insulin

FRIDAY, Aug. 16 (HealthDay News) -- Among women with gestational diabetes mellitus, those receiving metformin achieve lower mean glucose levels compared with those receiving insulin, but some require supplemental insulin therapy, according to research published in the July issue of the American Journal of Obstetrics & Gynecology.

Cristiane Pavão Spaulonci, M.D., of the University of São Paulo in Brazil, and colleagues randomly assigned women with gestational diabetes who failed to achieve glycemic control with diet and exercise to therapy with either metformin (47 patients) or insulin (47 patients).

The researchers found that mean glucose levels, amount of weight gain, and rate of neonatal hypoglycemia were all significantly lower in women receiving metformin compared with those receiving insulin. About 26 percent of the women receiving metformin needed supplemental insulin therapy to achieve glycemic control. Logistic regression analysis showed that earlier gestational age at diagnosis and higher mean pretreatment glucose level increased the probability of need for supplemental insulin.

"We believe that a long-term follow-up is needed, but a discussion by specialist teams on the use of metformin as a first-line drug in the treatment of patients with gestational diabetes would be of great usefulness for patients and doctors," the authors write.

Abstract
Full Text (subscription or payment may be required)



Copyright © 2013 HealthDay. All rights reserved.

July 22, 2014

Archive Search

By Keyword:
By Category:
By Topic:

Related Articles

National Survey Finds Most U.S. Physicians Are Satisfied

Decrease in HIV Diagnosis Rate From 2002 to 2011

Waistlines of U.S. Kids Seem to Be Holding Steady

Lanreotide Improves Survival With Enteropancreatic Tumors

Asthma Drug May Help Those With Chronic Hives

Good Response for Sofosbuvir + Ribavirin in HIV/HCV Coinfection