Contact HealthDay
Tel: 203.855.1400 or E-mail

News By Specialty

Allergy
Anesthesiology
Cardiology
Cosmetic Surgery
Critical Care
Dermatology
Diabetes & Endocrinology
Emergency Medicine
Family Practice
Gastroenterology
Geriatrics
Hematology & Oncology
HIV & AIDS
Infectious Disease
Internal Medicine
Nephrology
Neurology
Nursing
OBGYN & Women's Health
Ophthalmology
Orthopedics
Otolaryngology
Pain Management
Pathology
Pediatrics
Pharmacy
Psychiatry
Pulmonology
Radiology
Rheumatology
Surgery
Urology

Follow us on:

    


e-Healthcare Leadership Awards


Hormone Test May Indicate Risk of Gestational Diabetes
Low levels of adiponectin prior to pregnancy may identify women at high risk for GDM

THURSDAY, Aug. 29 (HealthDay News) -- Low serum concentrations of adiponectin prior to pregnancy may identify women at high risk for gestational diabetes mellitus (GDM), according to research published online Aug. 29 in Diabetes Care.

Monique Hedderson, Ph.D., of Kaiser Permanente Northern California in Oakland, and colleagues conducted a nested case-control study among women participating in the Kaiser Permanente Northern California Multiphasic Health Check-Up exam who had a subsequent pregnancy. Two controls matched by age and number of intervening pregnancies were selected for each of the 256 cases of women who developed GDM.

The researchers found that, after multivariable adjustment, the risk of GDM increased with decreasing quartile of serum adiponectin concentration (odds ratio [OR] and 95 percent confidence interval in descending order: 1.5 [0.7 to 2.9], 3.7 [1.9 to 7.2], and 5.2 [2.6 to 10.1]; P trend < 0.001) compared with the highest quartile. Compared with normal-weight women with total adiponectin levels above the median, overweight or obese women with levels below the median were at increased risk for GDM (OR, 6.7).

"In summary, after adjusting for potential confounding factors and clinical factors known to be related to insulin resistance, we found that low adiponectin concentrations, measured on average six years prior to pregnancy, were associated with a five-fold increased risk of GDM," the authors write.

Abstract
Full Text (subscription or payment may be required)



Copyright © 2013 HealthDay. All rights reserved.

April 24, 2014

Archive Search

By Keyword:
By Category:
By Topic:

Related Articles

FDA Proposes Accelerated Medical Device Approval Plan

Vitamin D Levels Linked to Activity Level in Severely Obese CME

Research Initiatives Demonstrate Ways to Speed Stroke Care

AAN: Mild Cognitive Impairment May Hasten Death

Rising Role Seen for Health Education Specialists

Irritable Bowel Ups Likelihood of Celiac Disease in Children