June 2019 Briefing - Cardiology

Here are what the editors at HealthDay consider to be the most important developments in Cardiology for June 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Medicare Advantage Patients Have Higher Readmission Rates

FRIDAY, June 28, 2019 (HealthDay News) -- Medicare Advantage patients have higher risk-adjusted hospital readmission rates than traditional Medicare patients for acute myocardial infarction, congestive heart failure, and pneumonia, according to a new study published online June 24 in the Annals of Internal Medicine.

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Myocardial Perfusion PET Predicts Cardiac Death in Diabetes

FRIDAY, June 28, 2019 (HealthDay News) -- Myocardial perfusion positron emission tomography (PET) imaging can improve risk prediction of cardiac death for patients with diabetes, according to a study published online June 27 in Radiology: Cardiothoracic Imaging.

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Infections Tied to Subsequent Risk for Acute Ischemic Stroke

FRIDAY, June 28, 2019 (HealthDay News) -- Different infection types, especially urinary tract infection (UTI), are associated with subsequent acute ischemic stroke, according to a study published online June 27 in Stroke.

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Three Interventions Could Cut Cardiovascular Deaths

THURSDAY, June 27, 2019 (HealthDay News) -- Lowering blood pressure, cutting sodium intake, and eliminating intake of trans fat could cut the incidence of premature death from cardiovascular disease by 94 million people worldwide during the next 25 years, according to a study published online June 10 in Circulation.

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First-Trimester BP Category Linked to Hypertensive Disorders

THURSDAY, June 27, 2019 (HealthDay News) -- First-trimester blood pressure (BP) category is associated with development of hypertensive disorders of pregnancy, according to a study published online June 27 in the American Journal of Obstetrics and Gynecology.

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Similar CV Event Rates Seen for Generic, Brand Levothyroxine

THURSDAY, June 27, 2019 (HealthDay News) -- Cardiovascular event rates are similar for patients with newly treated hypothyroidism receiving generic and brand levothyroxine (L-T4), according to a study published online April 26 in the Mayo Clinic Proceedings.

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Educational Attainment Positively Linked to CVD Risk Factors

WEDNESDAY, June 26, 2019 (HealthDay News) -- Educational attainment is positively associated with reduced smoking rates, depression, triglycerides, and heart disease, according to a study published online June 25 in PLOS Medicine.

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MSSP ACOs May Not Improve Spending, Quality of Care

WEDNESDAY, June 26, 2019 (HealthDay News) -- After adjustment for the nonrandom exit of clinicians, the Medicare Shared Savings Program (MSSP) is not associated with improvements in spending or quality, according to a study published online June 18 in the Annals of Internal Medicine.

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Americans Concerned About Clinician Burnout

WEDNESDAY, June 26, 2019 (HealthDay News) -- Nearly three-quarters of Americans are concerned about burnout among their clinicians, according to a survey released June 17 by the American Society of Health-System Pharmacists (ASHP).

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Short-Term Walking Intervention Offers Lasting Health Benefits

WEDNESDAY, June 26, 2019 (HealthDay News) -- Short-term primary care pedometer-based walking interventions can produce lasting health benefits, according to a study published online June 25 in PLOS Medicine.

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Older Kidney Donors With HTN at Higher Risk for ESKD Later

WEDNESDAY, June 26, 2019 (HealthDay News) -- Older kidney donors with hypertension have an increased risk for end-stage kidney disease (ESKD), but not mortality, through 15 years after donation, according to a study published online June 25 in the Clinical Journal of the American Society of Nephrology.

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Prevention Bundle May Cut Cardiac Device Infections

WEDNESDAY, June 26, 2019 (HealthDay News) -- Standardized protocols and bundles can improve infection prevention in the electrophysiology laboratory, according to a study published online June 4 in Infection Control & Hospital Epidemiology.

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Adherence Superior for Alternative Exercise Modalities in PAD

TUESDAY, June 25, 2019 (HealthDay News) -- For patients with intermittent claudication, completion and adherence rates are increased with use of alternative exercise modalities to walking, according to a review published online June 19 in the European Journal of Preventive Cardiology.

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Smoking Confers Greatest Risk for Major Heart Attack for Women

TUESDAY, June 25, 2019 (HealthDay News) -- Smoking confers a greater increase in ST-segment elevation myocardial infarction (STEMI) risk to women than men, according to a study published in the July 2 issue of the Journal of the American College of Cardiology.

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Adrenal Incidentalomas Rarely Grow, Change Hormone Function

MONDAY, June 24, 2019 (HealthDay News) -- Nonfunctioning adrenal tumors (NFATs) or adenomas causing mild autonomous cortisol excess (MACE) rarely show clinically relevant changes in size or hormone function, according to research published online June 25 in the Annals of Internal Medicine.

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Greater Long-Term Decline in Stroke Seen Among Older Adults

MONDAY, June 24, 2019 (HealthDay News) -- The decline in midlife ischemic strokes over time is less pronounced than the decline among older adults, according to a study published in the June issue of Stroke.

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Incident A-Fib Linked to Increased Dementia Risk

FRIDAY, June 21, 2019 (HealthDay News) -- Incident atrial fibrillation (AF) is associated with increased dementia risk in elderly populations, according to a study published online June 18 in the European Heart Journal.

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No Change Seen in Processed Meat Consumption by U.S. Adults

FRIDAY, June 21, 2019 (HealthDay News) -- During the last 18 years, there has been no change in consumption of processed meats among U.S. adults, according to a study published online June 21 in the Journal of the Academy of Nutrition and Dietetics.

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Some Heart Failure Patients May Benefit From CRT Defibrillator

THURSDAY, June 20, 2019 (HealthDay News) -- Cardiac resynchronization therapy with defibrillator (CRT-D) implantation is associated with better outcomes than an implantable cardioverter-defibrillator (ICD) for patients with nonspecific intraventricular conduction delay (NICD) but not for those with right bundle branch block (RBBB), according to a study published in the June 25 issue of the Journal of the American College of Cardiology.

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Restricting Blood Transfusions OK in Cardiac Surgery

THURSDAY, June 20, 2019 (HealthDay News) -- For high-risk patients undergoing cardiac surgery with cardiopulmonary bypass, a restrictive approach to red blood cell transfusions leads to fewer transfusions than a liberal approach, with no increase in the risk for acute kidney injury (AKI), according to a study published online June 20 in the Journal of the American Society of Nephrology.

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Meta-Analysis Does Not Link Vitamin D Supplements, Drop in MACE

THURSDAY, June 20, 2019 (HealthDay News) -- Vitamin D supplementation is not associated with a reduced risk for major adverse cardiovascular events, according to a meta-analysis published online June 19 in JAMA Cardiology.

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New England Journal of Medicine Picks New Editor-in-Chief

THURSDAY, June 20, 2019 (HealthDay News) -- The new editor-in-chief of the prestigious New England Journal of Medicine is Eric J. Rubin, M.D., Ph.D., who was selected after a worldwide search and plans to start in September, according to the Massachusetts Medical Society, which publishes the journal.

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Long Working Hours Linked to Increased Stroke Risk

THURSDAY, June 20, 2019 (HealthDay News) -- Individuals with long working hours (LWHs) have an increased risk for stroke, with a stronger correlation for those exposed to LWHs for 10 years or more, according to a study published online June 20 in Stroke.

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Health Care Workers With ARIs Often Work While Symptomatic

THURSDAY, June 20, 2019 (HealthDay News) -- Almost all health care workers (HCWs) with acute respiratory illness (ARI) report working at least one day while symptomatic, according to a study published online June 18 in Infection Control & Hospital Epidemiology.

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Chronic Distress After Heart Attack Ups Risk for Death

THURSDAY, June 20, 2019 (HealthDay News) -- Heart attack survivors with persistent emotional distress -- depression or anxiety -- are at a higher risk for death, according to a study published online June 3 in the European Journal of Preventive Cardiology.

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Risk Factors ID'd for Atrial Fibrillation With Type 1 Diabetes

THURSDAY, June 20, 2019 (HealthDay News) -- Older age, cardiovascular comorbidities, and renal complications increase the risk for atrial fibrillation (AF) in patients with type 1 diabetes, according to a study published online June 6 in Diabetes Care.

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CV MRI Noninferior to Invasive Angiography + FFR in Stable CAD

WEDNESDAY, June 19, 2019 (HealthDay News) -- Myocardial-perfusion cardiovascular magnetic resonance imaging (MRI) is noninferior to invasive angiography and fractional flow reserve (FFR) for guiding coronary revascularization in patients with stable angina and risk factors for coronary artery disease, according to a study published in the June 20 issue of the New England Journal of Medicine.

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Outpatient Office Visits Increased With Access to Patient Portal

WEDNESDAY, June 19, 2019 (HealthDay News) -- For patients with diabetes, use of a patient portal can increase engagement in outpatient visits, according to a study published online June 19 in PLOS ONE.

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Surgeons' Unprofessional Behavior Tied to Higher Complication Risk

WEDNESDAY, June 19, 2019 (HealthDay News) -- Patients whose surgeons have higher numbers of coworker reports about unprofessional behavior may be at increased risk for postsurgical complications, according to a study published online June 19 in JAMA Surgery.

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Midlife Cardiorespiratory Fitness Linked to Risk for COPD

WEDNESDAY, June 19, 2019 (HealthDay News) -- Midlife cardiorespiratory fitness (CRF) is associated with a reduced long-term risk for chronic obstructive pulmonary disease (COPD) and COPD death, according to a study published online June 17 in Thorax.

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Prophylactic IVC Filters Worsen Outcomes for Bariatric Surgery

WEDNESDAY, June 19, 2019 (HealthDay News) -- For patients undergoing bariatric surgery, use of prophylactic inferior vena cava filters (IVCFs) is associated with worse clinical outcomes and increased use of health care resources, according to a study published in the June 24 issue of JACC: Cardiovascular Interventions.

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Statins May Be Beneficial After Radiation to Thorax, Head, Neck

WEDNESDAY, June 19, 2019 (HealthDay News) -- For cardiac patients with thorax and head or neck cancer, statin use after radiation therapy is associated with a significant reduction in stroke incidence and a trend toward reduced cardiovascular and cerebrovascular events, according to a study published online June 19 in the Journal of the American Heart Association.

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Excess Weight Tied to Increased Risk for High BP in Young Children

WEDNESDAY, June 19, 2019 (HealthDay News) -- Four-year-olds with excess weight have an increased risk for high blood pressure at age 6 years, according to a study published online June 12 in the European Journal of Preventive Cardiology.

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Study Looks at Risk for Bleeding in Percutaneous Tx of PAD

WEDNESDAY, June 19, 2019 (HealthDay News) -- Major bleeding occurs in about 4 percent of lower-extremity peripheral vascular intervention (PVI) procedures, according to a study published online June 17 in JACC: Cardiovascular Interventions.

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Cardiovascular AEs Common With Carfilzomib in Multiple Myeloma

WEDNESDAY, June 19, 2019 (HealthDay News) -- For patients with relapsed multiple myeloma (MM), cardiovascular adverse events (CVAEs) are common with proteasome inhibitor therapy, particularly with carfilzomib, and are associated with inferior survival, according to a study published online June 12 in the Journal of Clinical Oncology.

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High Temperature Records Will be 'Smashed' in Coming Century

TUESDAY, June 18, 2019 (HealthDay News) -- Climate change will cause some regions of the world to "smash" high temperature records every year in the coming century, researchers warn. That will push "ecosystems and communities beyond their ability to cope," according to the authors of the study published online June 17 in Nature Climate Change.

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USPSTF Addresses Screening for Abdominal Aortic Aneurysm

TUESDAY, June 18, 2019 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommendations on screening for abdominal aortic aneurysm (AAA) vary with sex, age, smoking status, and family history. These recommendations form the basis of a draft recommendation statement published online June 18 by the USPSTF.

Draft Recommendation Statement
Draft Evidence Review
Comment on Recommendation

Patterns of Inpatient Opioid Use Linked to Long-Term Use

TUESDAY, June 18, 2019 (HealthDay News) -- Specific patterns of opioid administration to opioid-naive inpatients are associated with risk for long-term use after discharge, according to a study published online June 18 in the Annals of Internal Medicine.

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Coronary Artery Calcium Levels in Middle Age Tied to LV Function

TUESDAY, June 18, 2019 (HealthDay News) -- For middle-aged individuals, higher levels of coronary artery calcium (CAC) are associated with higher left ventricular (LV) mass and worse LV function, according to a study published online June 14 in Circulation: Cardiovascular Imaging.

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Drug Makers Challenge New Rule Requiring Drug Prices in TV Ads

MONDAY, June 17, 2019 (HealthDay News) -- Three large drug makers have launched a legal challenge against the Trump administration's rule requiring the prices of drugs to be included in television ads.

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Cognitive Decline Faster After Incident Coronary Heart Disease Event

MONDAY, June 17, 2019 (HealthDay News) -- Incident coronary heart disease (CHD) is associated with accelerated cognitive decline after, but not before, the event, according to a study published in the June 25 issue of the Journal of the American College of Cardiology.

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Nilvadipine Increases Cerebral Blood Flow in the Hippocampus

MONDAY, June 17, 2019 (HealthDay News) -- For patients with mild-to-moderate Alzheimer disease, treatment with nilvadipine lowers systolic blood pressure and increases cerebral blood flow (CBF) in the hippocampus, according to a study published online June 17 in Hypertension.

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Feelings of Powerlessness Tied to Delays in Seeking Care for Acute MI

MONDAY, June 17, 2019 (HealthDay News) -- Patients' perceived inability to act is associated with a delay in seeking medical care for acute myocardial infarction, according to a study published online May 27 in the European Journal of Cardiovascular Nursing.

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PPI Use for Up to Three Years Safe During Anticoagulant Tx

MONDAY, June 17, 2019 (HealthDay News) -- Use of pantoprazole for up to three years to prevent upper gastrointestinal events in patients receiving anticoagulant therapy with aspirin and/or rivaroxaban has a similar safety profile to placebo except for an increased risk for enteric infections, according to a study published online May 29 in Gastroenterology.

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Review Suggests More Sleep May Lower Cardiometabolic Risk

MONDAY, June 17, 2019 (HealthDay News) -- Increasing the length of nightly sleep may help reduce the risk for cardiovascular disease and metabolic disorders, according to a review published online June 5 in the Journal of Sleep Research.

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Cardiac Radiation Dose in NSCLC Predicts Mortality, Cardiac AEs

FRIDAY, June 14, 2019 (HealthDay News) -- Cardiac radiation dose exposure is a modifiable cardiac risk factor for major adverse cardiac events (MACE) and all-cause mortality (ACM) in patients with non-small cell lung cancer (NSCLC), according to a study published in the June 18 issue of the Journal of the American College of Cardiology.

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Undetected Dysglycemia Linked to MI, Periodontal Disease

FRIDAY, June 14, 2019 (HealthDay News) -- Undetected dysglycemia is associated with both myocardial infarction (MI) and periodontitis (PD), according to a study published online June 10 in Diabetes Care.

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More Aggressive Statin Tx Needed After Heart Attack in Young Patients

FRIDAY, June 14, 2019 (HealthDay News) -- The majority of young heart attack patients with familial hypercholesterolemia (FH) still have elevated cholesterol levels a year later, according to a study published in the May 21 issue of the Journal of the American College of Cardiology.

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ICU Care for STEMI Associated With Improved Mortality Rates

THURSDAY, June 13, 2019 (HealthDay News) -- Among ST-segment elevation myocardial infarction (STEMI) patients who could be treated in an intensive care unit (ICU) or a non-ICU unit, those treated in the ICU have improved mortality rates, according to a study published online June 4 in The BMJ.

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CDC: Prevalence of Meeting Exercise Guidelines Recently Increased

THURSDAY, June 13, 2019 (HealthDay News) -- From 2008 to 2017, there was an increase in the prevalence of meeting physical activity guidelines among adults living in rural and urban areas, according to research published in the June 14 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Obesity During Teen Years Tied to Stiffening of Arteries

THURSDAY, June 13, 2019 (HealthDay News) -- Persistently high fat mass during adolescence is associated with greater arterial stiffness, according to a study published online May 21 in The Lancet Child & Adolescent Health.

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Increases in Red Meat Intake Linked to Increased Mortality

THURSDAY, June 13, 2019 (HealthDay News) -- Increases in red meat consumption over eight years are associated with an increased mortality risk during the subsequent eight years, according to a study published online June 12 in The BMJ.

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Most Providers Unaware of Online Feedback About Themselves

WEDNESDAY, June 12, 2019 (HealthDay News) -- Many health care providers in the United Kingdom have little direct experience with online feedback, rarely encourage it, and often view it as having little value for improving the quality of health services, according to a study published online June 2 in the Journal of Health Services Research & Policy.

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Hot Water Therapy Aids Patients With Peripheral Arterial Disease

WEDNESDAY, June 12, 2019 (HealthDay News) -- Heat therapy can improve functional ability and also has potential to be an effective cardiovascular conditioning tool for people with peripheral arterial disease (PAD), according to a small study published online June 5 in the American Journal of Physiology-Heart and Circulatory Physiology.

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PDE5i Use Linked to Post-LVAD Right Heart Failure Events

WEDNESDAY, June 12, 2019 (HealthDay News) -- For left ventricular assist device (LVAD) recipients, those on phosphodiesterase-5 inhibitors (PDE5i) have a higher incidence of severe early right heart failure (RHF), according to a study published online June 11 in Circulation: Heart Failure.

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Mortality No Different With TAVR for Bicuspid, Tricuspid Stenosis

TUESDAY, June 11, 2019 (HealthDay News) -- For patients undergoing transcatheter aortic valve replacement (TAVR) for aortic stenosis, there is no significant difference in 30-day or one-year mortality for bicuspid or tricuspid aortic stenosis, according to a study published in the June 11 issue of the Journal of the American Medical Association.

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Higher Levels of Exercise in Childhood Improve Heart Health

TUESDAY, June 11, 2019 (HealthDay News) -- Engaging in higher levels of physical activity in childhood is associated with better cardiovascular health indicators, according to a study published online June 11 in Pediatrics.

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Polygenic Risk Score Reliably Predicts Coronary Artery Disease

TUESDAY, June 11 2019 (HealthDay News) -- Genome-wide polygenic risk scores (PRS) can predict coronary artery disease (CAD), according to a study published online June 11 in Circulation: Genomic and Precision Medicine.

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Untreated White Coat HTN May Increase Cardiovascular Risk

MONDAY, June 10, 2019 (HealthDay News) -- The risk for cardiovascular events and all-cause mortality is increased for individuals with untreated white coat hypertension (WCH) but not for those with treated white coat effect (WCE), according to a review published online June 11 in the Annals of Internal Medicine.

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Access to Health Care Has Little Impact on Longevity

MONDAY, June 10, 2019 (HealthDay News) -- Health care has modest effects on extending life expectancy in the United States, while behavioral and social determinants may have larger effects, according to a review published in the May/June issue of the Annals of Family Medicine.

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Antibiotic Prophylaxis Before Dental Work Often Unnecessary

FRIDAY, June 7, 2019 (HealthDay News) -- Antibiotic prophylaxis before dental procedures is unnecessary more than 80 percent of the time, according to a study published online May 31 in JAMA Network Open.

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Individualized Care Plans Advised for T2DM With Heart Failure

FRIDAY, June 7, 2019 (HealthDay News) -- Team-based care emphasizing development of individualized care plans is recommended for management of type 2 diabetes mellitus (T2DM) and heart failure, according to a scientific statement issued by the American Heart Association and Heart Failure Society of America and published online June 6 in Circulation.

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Rapid Cycling Work Roster Improves Resident Sleep Practices

THURSDAY, June 6, 2019 (HealthDay News) -- A rapidly cycling work roster (RCWR) is effective in reducing weekly work hours and the occurrence of >16 consecutive-hour shifts as well as improving sleep duration of resident physicians, according to a study published online May 20 in SLEEP.

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Survey Indicates Physician Misconduct Is Underreported

THURSDAY, June 6, 2019 (HealthDay News) -- Physician misconduct is being underreported and most Americans do not know where to file a complaint, according to a report published by the Federation of State Medical Boards (FSMB).

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Cardiovascular Health Poorer in Army Personnel Than Civilians

THURSDAY, June 6, 2019 (HealthDay News) -- Fewer U.S. Army personnel have ideal cardiovascular health (CVH) compared with their peers in the civilian population, according to a study published online June 5 in the Journal of the American Heart Association.

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Midlife Type 2 Diabetes May Up Later Risk for Cerebral Infarction

THURSDAY, June 6, 2019 (HealthDay News) -- Midlife type 2 diabetes is associated with an increased risk for cerebral infarction and cerebral artery occlusion in late life, according to a study published online June 6 in Diabetologia.

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Overdose-Death Donor Hearts Suitable for Transplant

THURSDAY, June 6, 2019 (HealthDay News) -- Recipient overall survival is similar for overdose-death donor (ODD) and non-ODD cardiac transplants, according to a study published online June 6 in the Annals of Thoracic Surgery.

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Increase in CV Mortality Smaller With Medicaid Expansion

WEDNESDAY, June 5, 2019 (HealthDay News) -- For middle-aged adults, counties in states that expanded Medicaid had a significantly smaller increase in cardiovascular mortality rates after expansion compared with states without expansion, according to a study published online June 5 in JAMA Cardiology.

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No Evidence of Legacy Effect Seen for Intensive Glucose Lowering

WEDNESDAY, June 5, 2019 (HealthDay News) -- There seems to be no evidence of a legacy effect or mortality benefit for intensive glucose control among military veterans with type 2 diabetes, according to a study published in the June 6 issue of the New England Journal of Medicine.

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Lowering Cholesterol Levels May Worsen Nerve Damage in T2DM

WEDNESDAY, June 5, 2019 (HealthDay News) -- Lowering serum cholesterol levels in patients with type 2 diabetes is associated with diabetic polyneuropathy (DPN), according to a study published online May 31 in JAMA Network Open.

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Carotid Atherosclerosis Predicts CV Events in Psoriatic Disease

WEDNESDAY, June 5, 2019 (HealthDay News) -- For patients with psoriatic disease (PsD), carotid atherosclerosis, as detected by ultrasound, predicts future incident cardiovascular events (CVEs), according to a study published online June 5 in Arthritis & Rheumatology.

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Burden of New-Onset A-Fib Considerable After TAVI, AVR

WEDNESDAY, June 5, 2019 (HealthDay News) -- The burden of new-onset atrial fibrillation is considerable following transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (AVR), and the odds of in-hospital mortality are increased with new-onset atrial fibrillation, according to a study published online June 3 in JAMA Internal Medicine.

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β-Blockers May Moderate Impact of Stress on Atrial Fibrillation

TUESDAY, June 4, 2019 (HealthDay News) -- β-blockers can attenuate the impact of anger or stress on atrial fibrillation (AF), according to a study published online June 4 in HeartRhythm.

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ACP Issues Position on Response to Physician Impairment

MONDAY, June 3, 2019 (HealthDay News) -- Providing assistance for physician impairment and rehabilitation is addressed in a position statement issued by the American College of Physicians and published online June 4 in the Annals of Internal Medicine.

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Guidelines Issued for Addressing Heart Disease Risk in HIV

MONDAY, June 3, 2019 (HealthDay News) -- People living with HIV (PLWH) have an increased risk for cardiovascular disease (CVD), a risk that needs appropriate management and treatment, according to a scientific statement issued by the American Heart Association and published online June 3 in Circulation.

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