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June 2020 Briefing - Critical Care

Here are what the editors at HealthDay consider to be the most important developments in Critical Care for June 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

U.S. Could See 100,000 New Cases of COVID-19 Each Day, Fauci Says

TUESDAY, June 30, 2020 (HealthDay News) -- Top U.S. infectious disease expert Anthony Fauci, M.D., warned Congress on Tuesday that COVID-19 infections could climb to 100,000 new cases daily unless ongoing outbreaks are contained.

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Heart Rhythm Disorders Seen in Critically Ill COVID-19 Patients

TUESDAY, June 30, 2020 (HealthDay News) -- Critically ill patients with COVID-19 are more likely to develop heart rhythm disorders than other hospitalized patients, according to a study published online June 22 in Heart Rhythm.

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Latinos Have High Rate of Positivity for SARS-CoV-2

TUESDAY, June 30, 2020 (HealthDay News) -- The rate of positivity for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is over 40 percent for Latinos in the Baltimore-Washington D.C. region, according to a research letter published online June 18 in the Journal of the American Medical Association.

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COVID-19 Drug Remdesivir Could Cost Up to $3,120 Per Patient

MONDAY, June 29, 2020 (HealthDay News) -- Gilead Sciences, the maker of remdesivir, the first drug that showed promise in treating COVID-19 infections, will charge U.S. hospitals $3,120 for a patient with private insurance, the company announced Monday.

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CDC: U.S. COVID-19 Rates Much Higher Than Reported

MONDAY, June 29, 2020 (HealthDay News) -- Actual COVID-19 infection rates in many areas of the United States are more than 10 times higher than reported rates, a U.S. Centers for Disease Control and Prevention study suggests.

The New York Times Article
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NY Health Care Workers Report Distress Related to COVID-19 Care

MONDAY, June 29, 2020 (HealthDay News) -- Many New York City health care workers are experiencing COVID-19-related psychological distress, especially nurses and advanced practice providers, according to a study published in the upcoming September-October issue of General Hospital Psychiatry.

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Antibody Tests ID COVID-19 Two to Three Weeks After Symptoms

MONDAY, June 29, 2020 (HealthDay News) -- Antibody testing may detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, with sensitivity peaking at three weeks since symptom onset, according to a review published online June 25 in the Cochrane Library.

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Factors Linked to Severe COVID-19 in Children Identified

MONDAY, June 29, 2020 (HealthDay News) -- COVID-19 generally causes mild disease in children, with 8 percent of children requiring intensive care unit (ICU) admission, according to a study published online June 25 in The Lancet Child & Adolescent Health.

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Altered Mental Status Not Uncommon in Severe COVID-19

MONDAY, June 29, 2020 (HealthDay News) -- Altered mental status is the second most common neurological presentation for patients with COVID-19, according to a study published online June 25 in The Lancet Psychiatry.

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Trump Administration Asks Supreme Court to Overturn Affordable Care Act

FRIDAY, June 26, 2020 (HealthDay News) -- The Trump administration has asked the Supreme Court to overturn the Affordable Care Act (ACA).

Washington Post Article

Serious Resident Errors Increase When Extended ICU Shifts Are Cut

FRIDAY, June 26, 2020 (HealthDay News) -- Resident physicians randomly assigned to schedules that eliminate extended shifts during their intensive care unit rotation make more serious errors than those with extended shifts, according to a study published in the June 25 issue of the New England Journal of Medicine.

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Physician's Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of June 22 to 26, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Black Americans More Likely to Know Someone Who Has Died of COVID-19

FRIDAY, June 26, 2020 (HealthDay News) -- Far more black Americans say they know someone personally who has died of COVID-19 than whites, a new poll finds.

Washington Post Article

U.S. Has Second Day of Record Rise in COVID-19 Cases; Young People Fueling Trend

FRIDAY, June 26, 2020 (HealthDay News) -- As the United States reported yet another record-breaking number of COVID-19 cases on Thursday, public health officials warned that younger Americans now account for an ever-growing percentage of infections.

The New York Times Article

Older Age, Obesity, Disability Tied to Severe COVID-19 in MS

FRIDAY, June 26, 2020 (HealthDay News) -- For patients with multiple sclerosis (MS), age, obesity, and high Expanded Disability Severity Scale score (EDSS) are significantly associated with increased risk for severe COVID-19, according to a study published online June 26 in JAMA Neurology.

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CDC Updates List of Who Is at Highest Risk for COVID-19

FRIDAY, June 26, 2020 (HealthDay News) -- The list of conditions that put people at risk for severe COVID-19 illness has been expanded by the U.S. Centers for Disease Control and Prevention.

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Colchicine May Improve Time to Clinical Deterioration in COVID-19

FRIDAY, June 26, 2020 (HealthDay News) -- Hospitalized patients with COVID-19 receiving colchicine have significantly improved time to clinical deterioration, according to a study published online June 24 in JAMA Network Open.

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Genomewide Level Associations Identified for Severe COVID-19

FRIDAY, June 26, 2020 (HealthDay News) -- Patients with COVID-19 and severe disease have associations at locus 3p21.31 and 9q34.2, which are significant at the genomewide level, according to a study published online June 17 in the New England Journal of Medicine.

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Texas Pauses Reopening as COVID-19 Cases Rise

THURSDAY, June 25, 2020 (HealthDay News) -- As COVID-19 cases surge in Texas, the state is pausing its reopening process and freeing up hospital beds for COVID-19 patients.

The New York Times Article

Risk for Hospitalization Up for Pregnant Women With COVID-19

THURSDAY, June 25, 2020 (HealthDay News) -- Among women of reproductive age with COVID-19, pregnant women are more likely to be hospitalized and to be admitted to the intensive care unit, according to research published in the June 26 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Sex, Ethnic Differential Patterns of COVID-19 Unexplained

THURSDAY, June 25, 2020 (HealthDay News) -- Sex and ethnicity differential patterns of COVID-19 positivity are not explained by cardiometabolic, socioeconomic, or behavioral factors, according to a study published online June 19 in the Journal of Public Health.

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Model May Help Predict Risk for Testing Positive for COVID-19

THURSDAY, June 25, 2020 (HealthDay News) -- It is possible to predict the likelihood of testing positive for COVID-19, according to a study published online June 10 in CHEST.

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Sanofi Speeds COVID-19 Vaccine Efforts

WEDNESDAY, June 24, 2020 (HealthDay News) -- French drugmaker Sanofi has shortened its timeline to get a COVID-19 vaccine on the market.

The New York Times Article

Experts Weigh in on Pace of Reopening, Preventive Measures

WEDNESDAY, June 24, 2020 (HealthDay News) -- As states across the country continue to move into different phases of reopening, many are questioning whether the rush to stabilize the economy will result in an influx of new COVID-19 infections. HD Live! sat down with Marjorie Jenkins, M.D., dean of the University of South Carolina School of Medicine Greenville, and Thomas Giordano, M.D., section chief of infectious diseases at the Baylor College of Medicine in Houston, to discuss the health care and economic uncertainty that faces the nation.

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Older Age, Black Race, Diabetes Up Hospitalization in COVID-19

WEDNESDAY, June 24, 2020 (HealthDay News) -- Characteristics that are independently associated with hospitalization for COVID-19 include older age, black race, and having diabetes mellitus, according to research published in the June 17 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Patients With COVID-19 Mount Acute Cortisol Stress Response

WEDNESDAY, June 24, 2020 (HealthDay News) -- Patients with COVID-19 mount a marked and appropriate acute cortisol stress response, according to a research letter published online June 19 in The Lancet Diabetes & Endocrinology.

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Tocilizumab Shows Promise for Treatment of COVID-19

WEDNESDAY, June 24, 2020 (HealthDay News) -- Use of tocilizumab to target cytokine release syndrome (CRS) seems beneficial for patients with COVID-19, according to a study published online June 15 in CHEST.

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Black, Hispanic Medicare Patients Much More Likely to Be Hospitalized With COVID-19

TUESDAY, June 23, 2020 (HealthDay News) -- Black Medicare recipients are nearly four times more likely and Hispanics are nearly two times more likely than whites to be hospitalized with COVID-19, according to the U.S. government.

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COVID-19 Vaccine May Be Available by Late 2020, Early 2021: Fauci

TUESDAY, June 23, 2020 (HealthDay News) -- There could be a COVID-19 vaccine by the end of this year or early next year, according to Anthony Fauci, M.D., infectious diseases chief at the U.S. National Institutes of Health.

AP News Article

Asthma Seems Not to Be Linked to COVID-19 Hospitalization

TUESDAY, June 22, 2020 (HealthDay News) -- Asthma seems not to be associated with COVID-19 hospitalization, according to a study published online June 9 in the Journal of Allergy and Clinical Immunology.

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Convalescent Plasma Safe for Diverse Patients With COVID-19

TUESDAY, June 23, 2020 (HealthDay News) -- Convalescent plasma seems safe for COVID-19 patients based on data from the first 20,000 transfused patients, according to a study published online June 9 in the Mayo Clinic Proceedings.

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COVID-19 Hospitalization Up With Prednisone in Rheumatic Disease

TUESDAY, June 23, 2020 (HealthDay News) -- For patients with rheumatic disease with COVID-19, glucocorticoids are associated with increased odds of hospitalization, according to a study published in the July issue of the Annals of Rheumatic Diseases.

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Costs for COVID-19 High With Consumer-Directed Health Plans

MONDAY, June 22, 2020 (HealthDay News) -- COVID-19 hospitalizations could result in high out-of-pocket spending for commercially insured consumer-directed health plan enrollees, according to a study published online June 15 in the American Journal of Preventive Medicine.

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Safety Climate Perceptions Linked to Health Provider Stress

MONDAY, June 22, 2020 (HealthDay News) -- Safety climate perceptions are associated with care practitioner-reported stress and job satisfaction, according to a study published in the May-June issue of the Journal of Healthcare Management.

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NIH Stops Hydroxychloroquine Trial

MONDAY, June 22, 2020 (HealthDay News) -- The National Institutes of Health announced Saturday that a clinical trial evaluating hydroxychloroquine for the treatment of COVID-19 has been stopped because the drug likely provides no benefit.

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Transmissibility of SARS-CoV-2 High Within Households

MONDAY, June 22, 2020 (HealthDay News) -- Severe acute respiratory syndrome coronavirus 2 has high transmissibility within households, according to a study published online June 17 in The Lancet Infectious Diseases.

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Many U.S. Counties Lack Infectious Disease Specialists

MONDAY, June 22, 2020 (HealthDay News) -- The distribution of infectious disease (ID) physicians in the United States is geographically skewed, with 90 percent of U.S. counties having below-average ID physician density or no ID physicians at all, according to a research letter published online June 3 in the Annals of Internal Medicine.

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Physician's Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of June 15 to 19, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Early Data Show No Protest-Related Increases in COVID-19 Infections

FRIDAY, June 19, 2020 (HealthDay News) -- Antiracism protests in the United States have not led to increases in new cases of the coronavirus that causes COVID-19, early data show.

The Wall Street Journal Article

Scientists Say Journal Should Retract Mask Study

FRIDAY, June 19, 2020 (HealthDay News) -- A study on the use of masks to protect against the new coronavirus should be retracted by the Proceedings of the National Academy of Sciences because it contains "egregious errors" and "verifiably false" statements, a group of scientists say in a letter to the journal's editors.

The New York Times Article

Stay-at-Home Orders Tied to Slowing of COVID-19 Hospitalizations

FRIDAY, June 19, 2020 (HealthDay News) -- Statewide stay-at-home orders are associated with decreases in COVID-19 hospitalizations, according to a research letter recently published in the Journal of the American Medical Association.

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Heart Transplant Patients May Have Higher COVID-19 Mortality

FRIDAY, June 19, 2020 (HealthDay News) -- Heart transplant patients admitted to the hospital with COVID-19 symptoms may be sicker than nontransplant patients, but they present with the same symptoms as the general population, according to a study recently published in the Journal of Cardiac Failure.

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22 Percent Worldwide at Increased Risk for Severe COVID-19

FRIDAY, June 19, 2020 (HealthDay News) -- About 22 percent of the global population has at least one underlying condition that places them at increased risk for severe COVID-19, according to a modeling study published online June 15 in The Lancet Global Health.

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Prone Position Ups Oxygenation in Patients With Severe COVID-19

FRIDAY, June 19, 2020 (HealthDay News) -- The use of the prone position for awake, spontaneously breathing patients with COVID-19-related severe hypoxemic respiratory failure is associated with improved oxygenation, according to a research letter published online June 17 in JAMA Internal Medicine.

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Isolation, Contact Tracing Combo Can Cut COVID-19 Transmission

FRIDAY, June 19, 2020 (HealthDay News) -- Combined isolation and tracing strategies can reduce COVID-19 transmission more than mass testing or self-isolation alone, according to a study published online June 16 in The Lancet Infectious Diseases.

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Nine Texas Mayors Ask Governor for Power to Mandate Face Masks

THURSDAY, June 18, 2020 (HealthDay News) -- Mayors in Houston, Dallas, Austin, San Antonio, and five other Texas municipalities want Gov. Greg Abbott to give them the power to require people to wear masks in public "where physical distancing cannot be practiced."

CNN Article

Sociodemographic Gaps Found in COVID-19 Incidence, Knowledge

THURSDAY, June 18, 2020 (HealthDay News) -- There are sociodemographic gaps in the reported incidence of COVID-19 and knowledge regarding its spread and symptoms, according to a study published online June 18 in JAMA Network Open.

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Face-Mask Use May Mitigate Spread of COVID-19

THURSDAY, June 18, 2020 (HealthDay News) -- Requiring face-mask use in public may help to mitigate the spread of COVID-19, according to a report published online June 16 in Health Affairs.

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Hyperglycemia Common in T1DM Patients With COVID-19

THURSDAY, June 18, 2020 (HealthDay News) -- Presentation patterns are similar in patients with type 1 diabetes admitted with confirmed or suspected COVID-19, according to a study published online June 5 in Diabetes Care.

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Survival Without Major Morbidity Up for Very Low Birth Weight

THURSDAY, June 18, 2020 (HealthDay News) -- For very low-birth-weight infants in California, there was a consistent increase in survival without major morbidity from 2008 to 2017, according to a study published online June 17 in Pediatrics.

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Clinical, Epidemiological Features of Pediatric SARS-CoV-2 ID'd

THURSDAY, June 18, 2020 (HealthDay News) -- Clinical and epidemiological characteristics of pediatric severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections are described in an article published online June 16 in PLOS Medicine.

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Strong Support Found for Protective Practices Related to COVID-19

WEDNESDAY, June 17, 2020 (HealthDay News) -- Most adults in New York City, Los Angeles, and the United States support stay-at-home orders and nonessential business closures during the COVID-19 pandemic and report always or often wearing face coverings in public areas, according to research published in the June 12 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Record-High Spikes in COVID-19 Cases Seen in Arizona, Florida, Texas

WEDNESDAY, June 17, 2020 (HealthDay News) -- After reopening, states such as Arizona, Florida, and Texas are all seeing record-high one-day increases in COVID-19 cases.

The New York Times Article

U.S. Insurers Should Not Charge Copays for COVID-19 Vaccine

WEDNESDAY, June 17, 2020 (HealthDay News) -- Health insurance companies are expected to cover vaccines for the new coronavirus without charging copays, U.S. officials say.

AP News Article

Risk for COVID-19 Reinfection Remains Unknown

WEDNESDAY, June 17, 2020 (HealthDay News) -- The potential risk for reinfection with COVID-19 remains a concern, but evidence is scarce, according to Jeffrey Shaman, Ph.D., director of the climate and health program at Columbia University, who recently spoke with HD Live! about his research and the risk for reinfection with COVID-19.

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CDC: Cumulative Incidence of COVID-19 403.6 Per 100,000 in U.S.

TUESDAY, June 16, 2020 (HealthDay News) -- The cumulative incidence of COVID-19 is 403.6 cases per 100,000 persons in the United States, and hospitalization and death rates are six and 12 times higher, respectively, for those with underlying conditions, according to research published in the June 15 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Hydroxychloroquine-Remdesivir Combo Dangerous for COVID-19 Patients

TUESDAY, June 16, 2020 (HealthDay News) -- In the treatment of COVID-19 patients, chloroquine phosphate or hydroxychloroquine sulfate should not be used with the experimental drug remdesivir because of a potentially unfavorable drug interaction, the U.S. Food and Drug Administration said.

More Information: FDA
Revised Fact Sheet for Health Care Providers: Remdesivir

Steroid May Reduce COVID-19 Death Risk by Up to One-Third

TUESDAY, June 16, 2020 (HealthDay News) -- The cheap and widely available steroid dexamethasone reduced the risk for death among seriously ill COVID-19 patients by up to a third, according to researchers in England.

AP News Article

Face Masks Most Effective Means to Avert COVID-19 Transmission

TUESDAY, June 16, 2020 (HealthDay News) -- Mandated face coverings represent the most effective means to prevent interhuman transmission of COVID-19, according to a study published online June 11 in the Proceedings of the National Academy of Sciences.

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Correlates of COVID-19 ID'd on American Indian Reservations

TUESDAY, June 16, 2020 (HealthDay News) -- The rate of COVID-19 cases is increased on American Indian reservations with larger proportions of homes lacking complete indoor plumbing, according to a study published in the July/August issue of the Journal of Public Health Management & Practice.

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COVID-19 Cases Rising in Many States as Reopening Continues

MONDAY, June 15, 2020 (HealthDay News) -- With most state reopenings well underway, many are now seeing alarming surges in COVID-19 cases, and New York Governor Andrew Cuomo warned that a return to lockdown for his state was possible.

CNN News Article

Black Americans Much More Likely to Have Lost Loved Ones to COVID-19

MONDAY, June 15, 2020 (HealthDay News) -- Black Americans are much more likely than other Americans to say a relative or close friend has died of COVID-19, surveys reveal.

AP News Article

Blood Donors Will Get Results of Coronavirus Antibody Test, Red Cross Says

MONDAY, June 15, 2020 (HealthDay News) -- The American Red Cross will test all blood, platelet, and plasma donations for COVID-19 antibodies so donors can learn whether they have been exposed to the new coronavirus.

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FDA Pulls Emergency Approval of Hydroxychloroquine for COVID-19

MONDAY, June 15, 2020 (HealthDay News) -- The U.S. Food and Drug Administration has withdrawn its emergency authorization for the use of chloroquine phosphate and hydroxychloroquine sulfate in the fight against COVID-19.

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Nonpharmaceutical Interventions Slow COVID-19 Growth

MONDAY, June 15, 2020 (HealthDay News) -- Nonpharmaceutical interventions have been beneficial for slowing COVID-19 growth on a global level and within Europe, according to two studies published online June 8 in Nature.

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Gastrointestinal Symptoms Not Uncommon With COVID-19

MONDAY, June 15, 2020 (HealthDay News) -- Approximately 12 percent of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection report gastrointestinal symptoms, according to a review published online June 11 in JAMA Network Open.

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COVID-19 Death Rate High for Patients With Thoracic Cancer

MONDAY, June 15, 2020 (HealthDay News) -- For patients with thoracic cancer, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with high mortality and low intensive care unit (ICU) admission, according to a study published online June 12 in The Lancet Oncology.

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Pediatric COVID-19 Symptoms Differ From Those Seen in Adults

MONDAY, June 15, 2020 (HealthDay News) -- Clinical manifestations of COVID-19 in children differ widely from adult cases, according to a review published online June 3 in Pediatric Pulmonology.

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Physician's Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of June 8 to 12, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Cesarean Delivery Tied to Clinical Deterioration in SARS-CoV-2

FRIDAY, June 12, 2020 (HealthDay News) -- Cesarean birth is associated with clinical deterioration in women with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and with an increased risk for neonatal intensive care unit (NICU) admission, according to a research letter published online June 8 in the Journal of the American Medical Association.

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Signs, Symptoms Vary Widely for Children Presenting With PIMS-TS

FRIDAY, June 12, 2020 (HealthDay News) -- Children presenting with pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; PIMS-TS) have a wide range of presenting symptoms, according to a study published online June 8 in the Journal of the American Medical Association.

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Risk or Fear of COVID-19 Should Not Delay Bystander CPR

FRIDAY, June 12, 2020 (HealthDay News) -- Bystander cardiopulmonary resuscitation (CPR) remains a vital, lifesaving endeavor for out-of-hospital cardiac arrest (OHCA), even during the COVID-19 pandemic, according to a study published online June 4 in Circulation.

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Many of the Initial COVID-19 Treatment Trials Poorly Designed

FRIDAY, June 12, 2020 (HealthDay News) -- Many clinical trials for COVID-19 treatments are limited by their design, with one-third excluding clinical end points, according to research published online June 9 in BMJ Open.

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Face-Mask Use by Public Can Mitigate Spread of COVID-19

THURSDAY, June 11, 2020 (HealthDay News) -- Face-mask use by the public, in combination with physical distancing and periods of lockdown, can mitigate the spread of the new coronavirus, according to a study published online June 10 in the Proceedings of the Royal Society A.

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First Large Clinical Trial of COVID-19 Vaccine in U.S. Could Begin in July

THURSDAY, June 11, 2020 (HealthDay News) -- A large clinical trial of the first U.S. COVID-19 vaccine could begin next month, according to Moderna Inc., which developed the vaccine with the U.S. National Institutes of Health.

AP News Article

Woman With Severe COVID-19 Receives Double-Lung Transplant

THURSDAY, June 11, 2020 (HealthDay News) -- A young COVID-19 survivor received a double-lung transplant to save her life in what is believed to be the first such surgery in the United States, Northwestern Medicine doctors report.

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COVID-19 Behavior Seems Consistent With Seasonal Virus

THURSDAY, June 11, 2020 (HealthDay News) -- Eight cities with substantial community outbreaks of COVID-19 are distributed along restricted latitude, temperature, and humidity measurements, consistent with behavior of a seasonal respiratory virus, according to a study published online June 11 in JAMA Network Open.

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Personal Protective Equipment Prevents SARS-CoV-2 Infection

THURSDAY, June 11, 2020 (HealthDay News) -- Appropriate personal protective equipment can protect frontline health care professionals who care for patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, according to a study published online June 10 in The BMJ.

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~18 Million at Increased COVID-19 Risk Underinsured in U.S.

THURSDAY, June 11, 2020 (HealthDay News) -- A total of 16.9 percent of those at increased risk for severe COVID-19 were inadequately insured at the start of the outbreak, according to a study published online June 10 in the Journal of General Internal Medicine.

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Risk Factors for Suicide ID'd in Health Care Professionals

THURSDAY, June 11, 2020 (HealthDay News) -- Modifiable and nonmodifiable risk factors for suicide have been identified among health care professionals, according to a study published online June 10 in JAMA Surgery.

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Acalabrutinib Promising for Treatment of Severe COVID-19

THURSDAY, June 11, 2020 (HealthDay News) -- For patients with severe COVID-19, treatment with acalabrutinib, a selective bruton tyrosine kinase (BTK) inhibitor, appears to improve oxygenation and reduce measures of inflammation, according to a study published in the June 5 issue of Science Immunology.

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Obesity Linked to Greater Severity of Pediatric COVID-19

WEDNESDAY, June 10, 2020 (HealthDay News) -- Obesity is the most common comorbidity among children and adolescents with COVID-19 and is associated with disease severity, according to a study published online June 3 in JAMA Pediatrics.

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VA May Not Have Enough PPE for Second COVID-19 Wave

WEDNESDAY, June 10, 2020 (HealthDay News) -- The U.S. Department of Veterans Affairs says it may not have enough personal protective equipment for medical staff if there is a second wave of the COVID-19 pandemic.

AP News Article

Study Will Assess Drugs Used to Treat Young COVID-19 Patients

WEDNESDAY, June 10, 2020 (HealthDay News) -- A study to assess several drugs currently being used to treat COVID-19 in infants, children, and teens has been announced by the U.S. National Institute of Child Health and Human Development (NICHD).

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Nine U.S. States Seeing Spikes in COVID-19 Hospitalizations

WEDNESDAY, June 10, 2020 (HealthDay News) -- In another troubling sign that the spread of COVID-19 might be accelerating, new U.S. data show hospitalizations in at least nine states have been on the rise since Memorial Day.

Washington Post Article

Troponin I Elevation Linked to Death in COVID-19 Patients

WEDNESDAY, June 10, 2020 (HealthDay News) -- Among patients hospitalized with COVID-19, troponin I elevation is associated with an increased risk for death, according to a study published online June 8 in the Journal of the American College of Cardiology.

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Record-High Numbers of New COVID-19 Cases Seen in 14 States, Puerto Rico

TUESDAY, June 9, 2020 (HealthDay News) -- A new analysis shows that parts of the country that had been spared the worst of the COVID-19 pandemic are now tallying record-high cases of new infections.

AP News Article
NBC News Article

WHO Backpedals on Claim That Asymptomatic Transmission of New Coronavirus Is Rare

TUESDAY, June 9, 2020 (HealthDay News) -- A claim that transmission of the COVID-19-causing coronavirus by people without symptoms is "very rare" was quickly reversed by the World Health Organization.

The New York Times Article

Thromboelastography Can Predict Blood Clots in COVID-19

TUESDAY, June 9, 2020 (HealthDay News) -- Hypercoagulable thromboelastography (TEG) can predict thrombotic events in patients with COVID-19 in the intensive care unit (ICU), according to a research letter published online June 5 in JAMA Network Open.

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COVID-19 Mortality Rate for Intubated Adults Lower Than Previously Reported

TUESDAY, June 9, 2020 (HealthDay News) -- Most patients with COVID-19 in the intensive care unit (ICU) recover, with a mortality rate of 35.7 percent for those on mechanical ventilation, according to a study published online May 26 in Critical Care Medicine.

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Partnership Would Bypass Drug Industry to Sell COVID-19 Vaccine

MONDAY, June 8, 2020 (HealthDay News) -- A partnership that would bypass the drug industry to sell a potential vaccine against the new coronavirus has been formed by a laboratory at Imperial College London.

The New York Times Article

Kawasaki-Like Disease More Common in Children of African Ancestry

MONDAY, June 8, 2020 (HealthDay News) -- A Kawasaki-like multisystem inflammatory syndrome, which is temporally associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among children in Paris, seems more common among children of African ancestry, according to a study published online June 3 in The BMJ.

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Anesthesiologists Shift Practice From OR to ICU During Pandemic

MONDAY, June 8, 2020 (HealthDay News) -- During the current new coronavirus pandemic, a large number of physician anesthesiologists pivoted from working in the operating room to treating COVID-19 patients in intensive care units, according to the results of an informal survey released by the American Society of Anesthesiologists (ASA).

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Physician's Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of June 1 to 5, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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NIH Head Fears Some Will Bypass a COVID-19 Vaccine

FRIDAY, June 5, 2020 (HealthDay News) -- Francis Collins, M.D., Ph.D., who heads the U.S. National Institutes of Health, is worried that antivaxxers will disrupt efforts to convince Americans to get vaccinated against the new coronavirus, CNN reported Thursday.

CNN Article

Nurse Understaffing May Up Risk for Multiple Organ Failure in ICU Patients

FRIDAY, June 5, 2020 (HealthDay News) -- Understaffing and increased nursing workload are associated with multiple organ failure in intensive care unit patients, according to a study published online June 3 in the Journal of Advanced Nursing.

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COVID-19 Mortality Higher for Those Not Taking Meds for Their HTN

FRIDAY, June 5, 2020 (HealthDay News) -- COVID-19 patients with hypertension have increased mortality risk, with significantly higher risk among those without antihypertensive treatment, according to a study published online June 4 in the European Heart Journal.

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Editorial

Postoperative Lung Complications Common in Patients With SARS-CoV-2

FRIDAY, June 5, 2020 (HealthDay News) -- About half of patients with perioperative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have postoperative pulmonary complications, which are associated with high 30-day mortality, according to a study published online May 29 in The Lancet.

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Editorial

COVID-19 Studies Retracted

THURSDAY, June 4, 2020 (HealthDay News) -- The Lancet and the New England Journal of Medicine each issued a retraction today on studies that evaluated COVID-19 data provided from the same private company.

The Lancet Retraction
New England Journal of Medicine Retraction

Acute Kidney Injury Common in COVID-19 Patients at NYC Hospital

THURSDAY, June 4, 2020 (HealthDay News) -- Patients admitted to a New York City hospital with COVID-19 faced major morbidity and mortality, with 78.0 percent of those admitted to the intensive care unit (ICU) developing acute kidney injury, according to a study published online May 29 in The BMJ.

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Systemic Inflammation Rare in Pediatric COVID-19 Patients

THURSDAY, June 4, 2020 (HealthDay News) -- Pediatric patients with COVID-19 rarely have systemic inflammation, according to a study published online June 3 in JAMA Network Open.

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Test of 10 Million in Wuhan Finds Few Infections

WEDNESDAY, June 3, 2020 (HealthDay News) -- Few new COVID-19 infections were found in the 10 million residents of Wuhan, China, after testing, the Associated Press reports.

AP News Article

Fauci Says Any COVID-19 Vaccine Would Be in Plentiful Supply by 2021

WEDNESDAY, June 3, 2020 (HealthDay News) -- According to Anthony Fauci, M.D., director of the U.S. National Institute of Allergy and Infectious Diseases, 100 million doses of a coronavirus vaccine will be available by year's end.

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COVID-19 Drug Studies Questioned

WEDNESDAY, June 3, 2020 (HealthDay News) -- Two premiere medical journals are questioning the validity of the data in two studies: one that showed the use of blood pressure drugs was safe in COVID-19 patients and another that showed the antimalarial drug hydroxychloroquine was dangerous, the Associated Press reported Wednesday.

AP News Article
Expression of Concern: The Lancet
Expression of Concern: NEJM

Young With Intellectual Disability More Likely to Die of COVID-19

WEDNESDAY, June 3, 2020 (HealthDay News) -- Age-related differences in COVID-19 trends are seen among those with intellectual and developmental disabilities (IDD), with a higher concentration of cases and increased case fatality in younger individuals with IDD, according to a study published online May 24 in the Disability and Health Journal.

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Chest CT Often Normal in Pediatric COVID-19 Patients

WEDNESDAY, June 3, 2020 (HealthDay News) -- Children with COVID-19 frequently have negative chest computed tomography (CT) findings, according to research published online May 22 in the American Journal of Roentgenology.

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SARS-CoV-2 Transmission in U.S. Likely Due to Single Lineage

TUESDAY, June 2, 2020 (HealthDay News) -- Sustained, community transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) possibly resulted from importation of a single lineage of virus from China between Jan. 18 and Feb. 9, 2020, according to research published in the May 29 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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BMI, Tracheal Intubation/Death Linked in Diabetes With COVID-19

TUESDAY, June 2, 2020 (HealthDay News) -- Body mass index (BMI) is associated with tracheal intubation and/or death within seven days among individuals with diabetes hospitalized for COVID-19, according to a study published online May 29 in Diabetologia.

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COVID-19 Took Toll on Mental Health of Chinese Physicians

TUESDAY, June 2, 2020 (HealthDay News) -- Physicians in China experienced a significant increase in mental health symptoms and fear of violence and a decline in mood after the outbreak of COVID-19, according to a research letter published online June 1 in JAMA Network Open.

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High Rates of DVT Seen in Critically Ill COVID-19 Patients

TUESDAY, June 2, 2020 (HealthDay News) -- Despite anticoagulant prophylaxis, many intensive care unit (ICU) patients with severe COVID-19-related pneumonia develop deep vein thrombosis, according to a research letter published online May 29 in JAMA Network Open.

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Guideline Details Pharmacologic Management of COPD

TUESDAY, June 2, 2020 (HealthDay News) -- In an American Thoracic Society clinical practice guideline, published in the May 1 issue of the American Journal of Respiratory and Critical Care Medicine, recommendations are presented for the pharmacologic management of patients with chronic obstructive pulmonary disease (COPD) complaining of exercise intolerance or dyspnea.

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Number of COVID-19-Infected Cruise Ship Passengers Underestimated

MONDAY, June 1, 2020 (HealthDay News) -- The majority of COVID-19-positive passengers and crew on one cruise ship were asymptomatic, according to a study published online May 27 in Thorax.

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Human Trial of Antibody Therapy to Treat COVID-19 Underway

MONDAY, June 1, 2020 (HealthDay News) -- The first human trial of an antibody therapy to treat COVID-19 is underway, CNN reported Monday.

CNN Article

Italian Health Care Workers' Mental Health Suffering During COVID-19

MONDAY, June 1, 2020 (HealthDay News) -- Health care workers (HCWs) in Italy who treated COVID-19 patients self-report substantial mental health symptoms, according to a research letter published online May 28 in JAMA Network Open.

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Significant Drop Seen in Type A Aortic Dissection After COVID-19

MONDAY, June 1, 2020 (HealthDay News) -- A significant decline was seen in the monthly surgical case volume of acute type A aortic dissection in New York City after COVID-19, according to a research letter published online May 14 in the Journal of the American College of Cardiology.

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ABCDE Bundle Can Reduce Ventilation Time for ICU Patients

MONDAY, June 1, 2020 (HealthDay News) -- Use of the awakening and breathing coordination, delirium monitoring/management, and early mobility (ABCDE) bundle can reduce ventilation time for patients admitted to the intensive care unit (ICU), according to a study recently published in AACN Advanced Critical Care.

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