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June 2020 Briefing - Hematology & Oncology

Here are what the editors at HealthDay consider to be the most important developments in Hematology & Oncology for June 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Good Diet May Cut Toxicity Risk in Treatment of Pediatric ALL

TUESDAY, June 30, 2020 (HealthDay News) -- Diets high in antioxidant-rich foods may cut the risk of developing bacterial infections or mucositis during the first phase of acute lymphoblastic leukemia (ALL) treatment in pediatric patients, according to a study published in the July 1 issue of the Journal of Clinical Oncology.

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Global Burden of Thyroid Cancer Is Increasing

TUESDAY, June 30, 2020 (HealthDay News) -- There is an increasing global burden of thyroid cancer, according to a study published online June 26 in JAMA Network Open.

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Incidence of VTE, Major Bleeding High in Primary CNS Lymphoma

MONDAY, June 29, 2020 (HealthDay News) -- The incidence of venous thromboembolism (VTE) and major bleeding is high among patients with primary central nervous system lymphoma (PCNSL), according to a study published online June 23 in Leukemia & Lymphoma.

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Government E-Cigarette Restrictions on Marketing Lower Use

MONDAY, June 29, 2020 (HealthDay News) -- Comprehensive provincial restrictions on electronic cigarette marketing are associated with lower levels of exposure to marketing and lower prevalence of e-cigarette use, according to a Canadian study published online June 29 in Pediatrics.

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Trump Administration Asks Supreme Court to Overturn Affordable Care Act

FRIDAY, June 26, 2020 (HealthDay News) -- The Trump administration has asked the Supreme Court to overturn the Affordable Care Act (ACA).

Washington Post Article

CDC Updates List of Who Is at Highest Risk for COVID-19

FRIDAY, June 26, 2020 (HealthDay News) -- The list of conditions that put people at risk for severe COVID-19 illness has been expanded by the U.S. Centers for Disease Control and Prevention.

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Complications After Colonoscopy Up for Those Aged ≥75

FRIDAY, June 26, 2020 (HealthDay News) -- For individuals undergoing outpatient colonoscopy, the risk of 30-day postcolonoscopy complications is increased for those aged ≥75 years, according to a study published online June 25 in JAMA Network Open.

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Minimally Invasive Hysterectomy Tied to Worse Cervical Cancer Outcomes

FRIDAY, June 26, 2020 (HealthDay News) -- Minimally invasive radical hysterectomy is associated with an elevated risk of recurrence and death compared with open surgery among patients undergoing radical hysterectomy for early-stage cervical cancer, according to research published online June 11 in JAMA Oncology.

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U.S. Burden of Skin and Subcutaneous Diseases Increasing

THURSDAY, June 25, 2020 (HealthDay News) -- The U.S. burden of skin and subcutaneous diseases is large but varies geographically, according to a study published online June 10 in JAMA Dermatology.

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J&J Ordered to Pay $2.1 Billion in Talcum Product Lawsuit

WEDNESDAY, June 24, 2020 (HealthDay News) -- Johnson & Johnson and a subsidiary must pay $2.1 billion in damages to women who said their ovarian cancers were caused by the company's baby powder and other talcum products, a Missouri appeals court ruled Tuesday.

The New York Times Article

Bayer to Pay $10 Billion to Settle Roundup Lawsuits

WEDNESDAY, June 24, 2020 (HealthDay News) -- Bayer has agreed to pay more than $10 billion to settle thousands of U.S. lawsuits alleging that its weedkiller Roundup causes cancer.

The New York Times Article

Quality of Life Worse for Cancer Patients During COVID-19

WEDNESDAY, June 24, 2020 (HealthDay News) -- Patients with stage III and IV cancer have worse quality of life during the COVID-19 pandemic, according to a research letter published online June 17 in Psycho-Oncology.

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African-American Participation Inadequate in Cancer Drug Trials

TUESDAY, June 23, 2020 (HealthDay News) -- African-Americans are underrepresented in clinical trials leading to approval of cancer medications, according to a research letter published online June 23 in the Annals of Internal Medicine.

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Racial Disparities Seen in PET/CT Imaging for Lung Cancer

TUESDAY, June 23, 2020 (HealthDay News) -- Black and Hispanic patients are less likely to undergo guideline-recommended imaging at diagnosis of non-small cell lung cancer, according to a study recently published in the Journal of the National Cancer Institute.

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Convalescent Plasma Safe for Diverse Patients With COVID-19

TUESDAY, June 23, 2020 (HealthDay News) -- Convalescent plasma seems safe for COVID-19 patients based on data from the first 20,000 transfused patients, according to a study published online June 9 in the Mayo Clinic Proceedings.

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More Sedentary Time Tied to Higher Risk for Cancer Mortality

TUESDAY, June 23, 2020 (HealthDay News) -- Greater sedentary time is independently associated with a higher cancer mortality risk, according to a study published online June 18 in JAMA Oncology.

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Safety Climate Perceptions Linked to Health Provider Stress

MONDAY, June 22, 2020 (HealthDay News) -- Safety climate perceptions are associated with care practitioner-reported stress and job satisfaction, according to a study published in the May-June issue of the Journal of Healthcare Management.

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Vitamin D May Cut Colitis Risk for Immune Checkpoint Inhibitors

MONDAY, June 22, 2020 (HealthDay News) -- For patients with melanoma treated with immune checkpoint inhibitors (ICIs), vitamin D intake is associated with a reduced risk for ICI colitis, according to a study published online June 22 in Cancer.

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Smoking Cessation Messages Focusing on Child Most Important

MONDAY, June 22, 2020 (HealthDay News) -- Smoking cessation messages that emphasize the impact on children and with outcomes focused on respiratory health, cancer, or general health are ranked as most important by parent smokers, according to a study published online June 22 in Pediatrics.

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Multilevel Interventions May Boost HPV Vaccination Rates

FRIDAY, June 19, 2020 (HealthDay News) -- Multilevel, provider-oriented interventions may improve human papillomavirus (HPV) vaccine series initiation and completion, according to a study published in the June 1 issue of Pediatrics.

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Cardioprotective Therapy Use Lower With Cancer History

THURSDAY, June 18, 2020 (HealthDay News) -- Cardioprotective therapies, especially statins and antiplatelets, are underutilized in patients with a history of cancer (CaHx), according to a research letter published in the June 1 issue of JACC: CardioOncology.

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Court Rules Against Drug Price Disclosures in TV Ads

THURSDAY, June 18, 2020 (HealthDay News) -- The U.S. government does not have the legal authority to force drug companies to disclose prices in their TV ads, a federal appeals court says.

AP News Article

Financial Hardship Linked to More ED Visits in Cancer Survivors

THURSDAY, June 18, 2020 (HealthDay News) -- Higher medical and nonmedical financial hardships are associated with a greater number of emergency department visits and lower receipt of some preventive services among cancer survivors, according to a study published in the July 1 issue of the American Journal of Preventive Medicine.

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Blood Donors Will Get Results of Coronavirus Antibody Test, Red Cross Says

MONDAY, June 15, 2020 (HealthDay News) -- The American Red Cross will test all blood, platelet, and plasma donations for COVID-19 antibodies so donors can learn whether they have been exposed to the new coronavirus.

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Aspirin Tied to Lasting Reduction in CRC Risk in Lynch Syndrome

MONDAY, June 15, 2020 (HealthDay News) -- For patients with Lynch syndrome, aspirin is associated with a reduced risk for colorectal cancer during long-term follow-up, according to a study published in the June 13 issue of The Lancet.

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COVID-19 Death Rate High for Patients With Thoracic Cancer

MONDAY, June 15, 2020 (HealthDay News) -- For patients with thoracic cancer, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with high mortality and low intensive care unit (ICU) admission, according to a study published online June 12 in The Lancet Oncology.

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Racial/Ethnic Disparities Seen in Economic Burden Due to Cancer Deaths

FRIDAY, June 12, 2020 (HealthDay News) -- There are considerable racial/ethnic disparities in the economic burden due to premature cancer deaths, according to a study published online June 3 in JNCI Cancer Spectrum.

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Considerable National Costs Attributed to Cancer Medical Care

FRIDAY, June 12, 2020 (HealthDay News) -- The national costs attributed to medical care for cancer are considerable and are projected to increase 34 percent by 2030 based on population growth, according to a study published online June 10 in Cancer Epidemiology, Biomarkers & Prevention.

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Risk Factors for Suicide ID'd in Health Care Professionals

THURSDAY, June 11, 2020 (HealthDay News) -- Modifiable and nonmodifiable risk factors for suicide have been identified among health care professionals, according to a study published online June 10 in JAMA Surgery.

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High-Risk Drinking Could Further Increase Liver Disease

WEDNESDAY, June 10, 2020 (HealthDay News) -- Without substantial changes in drinking, the disease burden and deaths due to alcohol-related liver disease will worsen in the United States through 2040, according to a study published in the June issue of The Lancet Public Health.

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Tumors of Embryonic Origin More Common in Children With Birth Defects

WEDNESDAY, June 10, 2020 (HealthDay News) -- For eight cancer types, there are differences in the frequencies of cancers in children with birth defects versus children with cancer but no birth defects, according to a study published online May 29 in Cancer.

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Breast Cancer Surgery Found to Be Safe in Older Women

WEDNESDAY, June 10, 2020 (HealthDay News) -- Breast cancer surgery is safe in women 70 years and older, according to a study published online June 2 in the British Journal of Surgery.

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Low-Dose Aspirin Lowers CVD Risk but Raises Bleeding Risk

WEDNESDAY, June 10, 2020 (HealthDay News) -- Low-dose aspirin significantly lowers cardiovascular disease (CVD) risk but increases the risk for bleeding, according to a review published online June 2 in the British Journal of Clinical Pharmacology.

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Percutaneous Cryoablation Treats Early-Stage Kidney Cancer

TUESDAY, June 9, 2020 (HealthDay News) -- Percutaneous cryoablation (PCA) for stage I renal cell carcinoma (RCC) results in good outcomes, with a 10-year disease-specific survival of 94 percent, according to a study published online June 9 in Radiology.

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Diet, Activity Guideline Updated by American Cancer Society

TUESDAY, June 9, 2020 (HealthDay News) -- The diet and physical activity guideline for the prevention of cancer has been updated by the American Cancer Society; the guideline was published online June 9 in CA: A Cancer Journal for Clinicians.

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Prostate Cancer Trial Participants Overwhelmingly White

TUESDAY, June 9, 2020 (HealthDay News) -- Prostate cancer clinical trial participants are overwhelmingly white, according to a study published online June 5 in Cancer Epidemiology, Biomarkers & Prevention.

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Thromboelastography Can Predict Blood Clots in COVID-19

TUESDAY, June 9, 2020 (HealthDay News) -- Hypercoagulable thromboelastography (TEG) can predict thrombotic events in patients with COVID-19 in the intensive care unit (ICU), according to a research letter published online June 5 in JAMA Network Open.

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Educational Video May Effectively Inform Families About Hospice Care

MONDAY, June 8, 2020 (HealthDay News) -- An educational video may better inform advanced cancer patients and their caregivers about hospice care, according to a study published online June 8 in Cancer.

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Racial Differences Seen in Time to Treatment for Melanoma

FRIDAY, May 5, 2020 (HealthDay News) -- Black patients are more likely to experience a longer delay from diagnosis to surgery versus white patients with melanoma, according to a study recently published in the Journal of the American Academy of Dermatology.

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Certain Tumor Markers Also Tied to Heart Failure Outcomes

FRIDAY, June 5, 2020 (HealthDay News) -- Tumor biomarkers are independently associated with measures of heart failure severity and outcomes, according to a study published online May 5 in the Journal of Internal Medicine.

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Most Teens Recover Iron Stores One Year After Whole Blood Donation

FRIDAY, June 5, 2020 (HealthDay News) -- Most, but not all, teenagers have adequate iron stores within 12 months after whole blood (WB) or double red blood cell (2RBC) donation, according to a study published online June 5 in Pediatrics.

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In AML, Time From Diagnosis to Treatment Not Linked to Survival

THURSDAY, June 4, 2020 (HealthDay News) -- For patients with newly diagnosed acute myeloid leukemia, the time from diagnosis to treatment start (TDT) for intensive treatment is not associated with overall survival, according to a study published online June 4 in Blood.

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Rituximab + Chemo Ups Survival in Pediatric B-Cell Non-Hodgkin Lymphoma

THURSDAY, June 4, 2020 (HealthDay News) -- For children and adolescents with high-grade, high-risk, mature B-cell non-Hodgkin lymphoma, rituximab added to standard lymphomes malins B (LMB) chemotherapy prolongs event-free survival, according to a study published in the June 4 issue of the New England Journal of Medicine.

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Adherence to Diabetes Meds May Cut Mortality in Colorectal Cancer

TUESDAY, June 2, 2020 (HealthDay News) -- For patients with colorectal cancer and diabetes, adherence to diabetes medication is associated with better survival, according to a study published online June 1 in Cancer, Epidemiology, Biomarkers & Prevention.

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Insulin Resistance May Add to Racial Disparity in Breast Cancer Prognosis

MONDAY, June 1, 2020 (HealthDay News) -- Insulin resistance is one factor mediating part of the association between race and poor prognosis in breast cancer, according to a study published online May 12 in Breast Cancer Research.

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Radiation Oncology Clinic Visits Down Due to COVID-19

MONDAY, June 1, 2020 (HealthDay News) -- Despite adoption of enhanced safety measures, radiation oncologists have seen a drop in patient volumes due to the COVID-19 pandemic, according to the results of a survey released May 20 by the American Society for Radiation Oncology (ASTRO).

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