April 2019 Briefing - HIV & AIDS

Here are what the editors at HealthDay consider to be the most important developments in HIV & AIDS for April 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Gender Differences Seen in Adverse Drug Reactions

FRIDAY, April 26, 2019 (HealthDay News) -- The risk for adverse drug reactions (ADRs) may be higher for women, even when accounting for gender differences in drug use, according to a study published online April 2 in the British Journal of Clinical Pharmacology.

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National Hand Hygiene Initiative Successful in Australia

FRIDAY, April 19, 2019 (HealthDay News) -- The National Hand Hygiene Initiative (NHHI) has successfully sustained improvement in hand hygiene compliance, according to a study recently published in The Lancet Infectious Diseases and presented at the European Congress of Clinical Microbiology & Infectious Diseases, held from April 13 to 16 in Amsterdam.

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Loan Forgiveness, Educational Debt May Affect Practice Patterns

FRIDAY, April 19, 2019 (HealthDay News) -- Increased educational debt appears to directly influence physician practice choice, according to a study published in the April issue of the Journal of the American Osteopathic Association.

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Naltrexone Implant Helps HIV Patients Prevent Opioid Relapse

FRIDAY, April 19, 2019 (HealthDay News) -- Slow-release implantable naltrexone is associated with better outcomes than the oral drug for HIV-positive patients with an opioid addiction, according to a study published in the April issue of The Lancet HIV.

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Sixty People Charged in Massive Opioid Painkiller Investigation

THURSDAY, April 18, 2019 (HealthDay News) -- Fifty-three medical professionals, including 31 doctors, are among the 60 people charged by U.S. authorities for their alleged involvement in the illegal prescribing and distribution of opioid painkillers.

AP News Article

UB-421 Monotherapy Maintains HIV Viral Suppression

THURSDAY, April 18, 2019 (HealthDay News) -- Monotherapy with UB-421 antibody, which blocks the HIV virus-binding site on human CD4+ T-cells, maintains viral suppression for up to 16 weeks in HIV-infected persons undergoing analytic treatment interruption, according to a study published in the April 18 issue of the New England Journal of Medicine.

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Standardizing Demographics Ups Accuracy of Patient Matching

MONDAY, April 15, 2019 (HealthDay News) -- Standardizing demographic data can improve the accuracy of patient matching, according to a study published in the May issue of the Journal of the American Medical Informatics Association.

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Prevalence of Extragenital STDs High in Men Who Have Sex With Men

FRIDAY, April 12, 2019 (HealthDay News) -- Extragenital (rectal and pharyngeal) chlamydia and gonorrhea are prevalent among men who have sex with men (MSM), according to research published in the April 12 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Domestic Responsibilities Tied to Physician Mothers' Satisfaction

THURSDAY, April 11, 2019 (HealthDay News) -- For physician mothers in procedural specialties, being responsible for five or more domestic tasks is associated with an increased likelihood of career dissatisfaction, according to a study published online April 10 in JAMA Surgery.

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STI Incidence Up After Receipt of HIV Preexposure Prophylaxis

WEDNESDAY, April 10, 2019 (HealthDay News) -- For gay and bisexual men, receipt of HIV preexposure prophylaxis (PrEP) is associated with an increase in sexually transmitted infections (STIs), according to a study published in the April 9 issue of the Journal of the American Medical Association.

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First Two-Drug Regimen Approved for HIV-1 Treatment

MONDAY, April 8, 2019 (HealthDay News) -- The U.S. Food and Drug Administration has announced the approval of Dovato (dolutegravir and lamivudine), the first approved two-drug, fixed-dose, complete regimen for adults with HIV-1 who have not been previously treated with antiretroviral medication.

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Alcohol, Drug Misuse Tied to Long-Term Health Problems

MONDAY, April 8, 2019 (HealthDay News) -- More than one-third of U.S. adults in recovery for alcohol and other drug (AOD) use have health problems related to previous substance use, according to a study published online March 16 in the Journal of Addiction Medicine.

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CDC: TB Incidence Declined Slightly in United States in 2017

MONDAY, April 8, 2019 (HealthDay News) -- In 2017, tuberculosis (TB) incidence declined in the United States and modest progress was made toward global TB elimination, according to two studies published in the March 21 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Depressive Symptoms May Up Risk for Death in HIV+ Veterans

FRIDAY, April 5, 2019 (HealthDay News) -- Among U.S. veterans with HIV infection, depressive symptoms are associated with a significantly increased risk for mortality, but depression is not, according to a study published online March 29 in HIV Medicine.

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Americans Borrowed $88 Billion in Past Year to Pay for Health Care

TUESDAY, April 2, 2019 (HealthDay News) -- About one in eight Americans borrowed a total of $88 billion in the past year to pay for health care, a new West Health-Gallup survey shows.

CNN Article
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Dolutegravir Feasible for HIV Tx in Women of Childbearing Age

TUESDAY, April 2, 2019 (HealthDay News) -- Dolutegravir should be considered for antiretroviral therapy (ART) in treating HIV in women of childbearing potential in resource-limited settings, despite its associated risk for neural tube defects, according to a study published online April 2 in the Annals of Internal Medicine.

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Over-the-Counter Meds Save Health Care System Money

TUESDAY, April 2, 2019 (HealthDay News) -- On average, each dollar spent on over-the-counter (OTC) medicines saves the U.S. health care system $7.20, totaling nearly $146 billion in annual savings, according to a report released March 18 by the Consumer Healthcare Products Association (CHPA).

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Doctors Unclear on Legal Obligations in Caring for Patients With Disability

MONDAY, April 1, 2019 (HealthDay News) -- Practicing physicians might not understand their legal responsibilities when caring for people with disability, which may contribute to inequalities in their care, according to a study published online April 1 in Health Affairs.

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