Can You Get COVID-19 Again? Replay our May 22 HDLive!

Follow Our Live Coverage of COVID-19 Developments

April 2020 Briefing - Pharmacy

Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for April 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Symptomatic Health Care Staff in U.K. Screened for COVID-19

THURSDAY, April 30, 2020 (HealthDay News) -- Screening symptomatic health care workers for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is feasible during the pandemic, according to a research letter published online April 22 in The Lancet.

Abstract/Full Text (subscription or payment may be required)

Remdesivir May Accelerate Recovery From Severe COVID-19

THURSDAY, April 30, 2020 (HealthDay News) -- Remdesivir may speed time to clinical improvement for patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, although results are conflicting, according to a study published online April 29 in The Lancet and press releases issued regarding a National Institutes of Health (NIH)-sponsored study.

Abstract/Full Text - Wang (subscription or payment may be required)
Editorial (subscription or payment may be required)
Press Release

Psoriasis Tied to Higher Alzheimer Disease Risk

THURSDAY, April 30, 2020 (HealthDay News) -- The incidence of Alzheimer disease (AD) is significantly higher in patients with psoriasis versus individuals without psoriasis, according to a Korean study published online April 15 in Scientific Reports.

Abstract/Full Text (subscription or payment may be required)

David Shulkin, M.D., on COVID-19 Financial Consequences for Health Care System

MONDAY, April 27, 2020 (HealthDay News) -- Health care organizations are facing hard financial decisions amid the COVID-19 pandemic, but an end is in sight as some are beginning to slowly open back up around the country, according to David Shulkin, M.D. Shulkin, who served as ninth secretary for Veterans Affairs and is former president and CEO of Beth Israel Medical Center in New York, spoke with HealthDay during a live stream on the HealthDay YouTube channel and live blog.

More Information
KIMT3 Article

USPSTF: Behavioral Interventions Likely Prevent Tobacco Use

WEDNESDAY, April 29, 2020 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) concludes that primary care-feasible behavioral interventions have a moderate net benefit for preventing tobacco use in children. These findings form the basis of a final recommendation statement, published online April 28 in the Journal of the American Medical Association.

Evidence Report (subscription or payment may be required)
Recommendations (subscription or payment may be required)
Editorial (subscription or payment may be required)

Thromboembolic Complications in COVID-19 Discussed

WEDNESDAY, April 29, 2020 (HealthDay News) -- Prevention, diagnosis, and therapeutic management of thromboembolic complications in COVID-19 are discussed in a report published online April 23 in Radiology.

Abstract/Full Text

Low Vitamin D, Smoking Predict Worse Cognitive Function in MS

WEDNESDAY, April 29, 2020 (HealthDay News) -- For multiple sclerosis (MS) patients with clinically isolated syndrome, lower vitamin D and smoking predict worse long-term cognitive function and neuronal integrity, according to a study published online April 16 in Neurology.

Abstract/Full Text (subscription or payment may be required)

National Coronavirus Testing Strategy Announced as U.S. Cases Top 1 Million

TUESDAY, April 28, 2020 (HealthDay News) -- While health experts continued to call for a national strategy to test more Americans for coronavirus, President Donald Trump on Monday announced a "blueprint" for boosting testing capacity as some states began reopening their economies.

Washington Post Article
CBS News Article
New York Times Article

Low Vitamin D May Reduce Survival for Some With Multiple Myeloma

TUESDAY, April 28, 2020 (HealthDay News) -- Vitamin D deficiency is associated with reduced overall survival for patients with multiple myeloma (MM), with a differential effect across race, according to a study published online April 21 in Blood Advances.

Abstract/Full Text

Adding High-Dose Chloroquine Not Advised for Severe COVID-19

TUESDAY, April 28, 2020 (HealthDay News) -- High-dosage chloroquine diphosphate (CQ) has potential safety hazards when used as adjunctive therapy for patients hospitalized with severe COVID-19, according to a study published online April 24 in JAMA Network Open.

Abstract/Full Text
Editorial

Diabetes Medication Prescribing Increased 2003 to 2016

TUESDAY, April 28, 2020 (HealthDay News) -- Pharmacologic treatment for type 2 diabetes increased from 2003 to 2016, according to a study published online March 31 in Diabetes Care.

Abstract/Full Text (subscription or payment may be required)

FDA Warns of Bogus Claims by Makers of Hand Sanitizer

MONDAY, April 27, 2020 (HealthDay News) -- Some companies are selling hand sanitizers with unproven claims that they will protect against COVID-19, the U.S. Food and Drug Administration warns.

More Information

WHO: No Evidence COVID-19 Survivors Cannot Be Reinfected

MONDAY, April 27, 2020 (HealthDay News) -- There is "no evidence" that people who have recovered from COVID-19 cannot be reinfected with the severe acute respiratory syndrome coronavirus 2, according to the World Health Organization.

CBS News Article
CNN Article
More Information: CDC

Direct Medical Costs of COVID-19 Infection Are Considerable

MONDAY, April 27, 2020 (HealthDay News) -- A single symptomatic COVID-19 infection results in direct medical costs of $3,045 in the United States, according to a study published online April 23 in Health Affairs.

Abstract/Full Text

Racial Differences Found in Managing Children's Pain From Broken Bones

MONDAY, April 27, 2020 (HealthDay News) -- There are racial differences in pain management and pain outcomes for children seen in the emergency department for long-bone fractures, according to a study published online April 20 in Pediatrics.

Abstract/Full Text

Physician's Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of April 20 to 24, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article

Premature Posting of Remdesivir Findings Were 'Inconclusive'

FRIDAY, April 24, 2020 (HealthDay News) -- Inconclusive findings from a study investigating the antiviral drug remdesivir as a treatment for COVID-19 were posted to the World Health Organization website "prematurely," drug maker Gilead Sciences said Thursday.

CNN Article

FDA Warns About Treating COVID-19 With Unproven Drugs

FRIDAY, April 24, 2020 (HealthDay News) -- Malaria drugs touted by some as potential "game changers" against COVID-19 are actually too dangerous for general use, the U.S. Food and Drug Administration warned Americans on Friday.

More Information

COVID-19-Linked Changes Reported in Rheumatic Disease Patient Care

FRIDAY, April 24, 2020 (HealthDay News) -- Changes to health care have been reported among patients with rheumatic diseases during the COVID-19 pandemic, according to a study published online April 20 in ACR: Open Rheumatology.

Abstract/Full Text (subscription or payment may be required)

Low Doses of Bevacizumab Tested for Retinopathy of Prematurity

FRIDAY, April 24, 2020 (HealthDay News) -- For treatment of retinopathy of prematurity (ROP), 0.004 mg may be the lowest effective dose of bevacizumab, according to a study published online April 23 in JAMA Ophthalmology.

Abstract/Full Text

Review: MMR, MMRV, MMR+V Vaccines Are Effective, Safe

FRIDAY, April 24, 2020 (HealthDay News) -- Measles, mumps, and rubella (MMR) vaccines and MMR vaccines with varicella are effective and safe, according to an updated review published online April 20 in the Cochrane Database of Systematic Reviews.

Abstract/Full Text

White House Announces Payment Plan for Uninsured COVID-19 Patients

THURSDAY, April 23, 2020 (HealthDay News) -- A plan to begin paying hospitals and doctors who treat uninsured COVID-19 patients was announced by U.S. Health and Human Services Secretary Alex Azar on Wednesday.

AP News Article

'Health Force' to Combat Pandemic Proposed by U.S. Senators

THURSDAY, April 23, 2020 (HealthDay News) -- A bill to create a "Health Force" to help combat the U.S. COVID-19 outbreak has been announced by two Democratic senators.

NBC News Article

ACEIs/ARBs Not Linked to Severity or Mortality of COVID-19

THURSDAY, April 23, 2020 (HealthDay News) -- For patients with hypertension hospitalized with COVID-19 infections, angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin receptor blockers (ARBs) are not associated with the severity or mortality of COVID-19, according to a brief report published online April 23 in JAMA Cardiology.

Abstract/Full Text

Clascoterone Cream Safe, Effective for Acne Treatment

THURSDAY, April 23, 2020 (HealthDay News) -- Clascoterone cream, 1 percent, appears to be safe and effective for the treatment of acne, according to a study published online April 22 in JAMA Dermatology.

Abstract/Full Text
Editorial

Lopinavir/Ritonavir, Umifenovir Ineffective for Mild COVID-19

THURSDAY, April 23, 2020 (HealthDay News) -- For patients hospitalized with mild/moderate COVID-19, lopinavir/ritonavir (LPV/r) or umifenovir (Arbidol) monotherapy offers little benefit, according to a study published online April 17 in Med.

Abstract/Full Text

Higher Manganese Intake May Be Tied to Lower Type 2 Diabetes Risk

THURSDAY, April 23, 2020 (HealthDay News) -- Higher intake of manganese is associated with a lower type 2 diabetes risk among postmenopausal women, independent of known risk factors, according to a study published online April 15 in Diabetes Care.

Abstract/Full Text (subscription or payment may be required)

Hydroxychloroquine Seems Not to Cut Ventilator Use in COVID-19

WEDNESDAY, April 22, 2020 (HealthDay News) -- There is no evidence that use of hydroxychloroquine alone (HC) or with azithromycin (HC+AZ) reduces the risks for mechanical ventilation or death from any cause in patients hospitalized with COVID-19, according to a study that has not yet been peer reviewed and was posted online April 21 at medRxiv.org.

Abstract/Full Text (subscription or payment may be required)

Rapid COVID-19 Test Can Produce False Negatives

WEDNESDAY, April 22, 2020 (HealthDay News) -- A widely used rapid COVID-19 test can produce false negatives if a certain solution is used to move or store patients' samples, the test's maker said.

CNN Article

Expert Panel: There Are No Proven Drug Treatments for COVID-19

WEDNESDAY, April 22, 2020 (HealthDay News) -- There is no proven drug treatment for COVID-19 patients, according to a panel of experts convened by the U.S. National Institute of Allergy and Infectious Diseases.

The New York Times Article

IBD Symptoms in Pregnancy Tied to Higher C-Section Rate, IUGR

WEDNESDAY, April 22, 2020 (HealthDay News) -- Women with inflammatory bowel disease (IBD) have lower pregnancy rates, and those with uncontrolled disease are at increased risk for adverse outcomes, according to a study published online April 7 in Alimentary Pharmacology and Therapeutics.

Abstract/Full Text

FDA Authorizes COVID-19 Test That Uses Samples Collected at Home

TUESDAY, April 21, 2020 (HealthDay News) -- The U.S. Food and Drug Administration has approved emergency use of the first COVID-19 test that enables patients to take samples at home.

More Information

LA County COVID-19 Infections Far Exceed Number of Confirmed Cases

TUESDAY, April 21, 2020 (HealthDay News) -- An early analysis of antibody testing from Los Angeles County reveals a COVID-19 infection rate that is up to 55 times the number of confirmed COVID-19 cases.

More Information

Physicians Report Low Interest in Opioid Use Disorder Meds

TUESDAY, April 21, 2020 (HealthDay News) -- Few primary care physicians report interest in treating patients with opioid use disorder (OUD), according to a research letter published online April 21 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Cardiac Cath Lab STEMI Activations Drop During Pandemic

TUESDAY, April 21, 2020 (HealthDay News) -- During the COVID-19 pandemic, there has been a 38 percent reduction in U.S. cardiac catheterization laboratory ST-segment elevation myocardial infarction (STEMI) activations, according to a research letter published online April 10 in the Journal of the American College of Cariology.

Abstract/Full Text (subscription or payment may be required)

Lab Protocol Failures Led to Ineffective COVID-19 Tests From CDC

MONDAY, April 20, 2020 (HealthDay News) -- The first COVID-19 tests in the United States were ineffective due to poor laboratory practices at the U.S. Centers for Disease Control and Prevention, the U.S. Food and Drug Administration said.

The New York Times Article

Benefit of Social Distancing Outweighs Economic Impact

MONDAY, April 20, 2020 (HealthDay News) -- The economic benefits of lives saved through social distancing substantially outweigh the value of the projected losses to the U.S. economy, according to a study to be published in a forthcoming issue of the Journal of Benefit-Cost Analysis.

Abstract/Full Text (subscription or payment may be required)

Physician's Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of April 13 to 17, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article

CDC Looks at Transmission of COVID-19 to Health Care Workers

FRIDAY, April 17, 2020 (HealthDay News) -- Transmission of coronavirus disease 2019 (COVID-19) to health care personnel (HCP) is explored in two studies published in the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text - Heinzerling
Abstract/Full Text - Burrer

IDSA Issues Rapid Guidelines for Treatment of COVID-19

FRIDAY, April 17, 2020 (HealthDay News) -- In rapid guidelines issued by the Infectious Diseases Society of America (IDSA), recommendations are presented for the treatment and management of coronavirus disease 2019 (COVID-19).

Abstract/Full Text

Probiotics May Help Reduce Mild-to-Moderate Acne Symptoms

FRIDAY, April 17, 2020 (HealthDay News) -- The use of probiotics as an adjunct therapy may help in the management of acne vulgaris, according to a review published online April 7 in Dermatologic Therapy.

Abstract/Full Text (subscription or payment may be required)

Recurrent Winter Outbreaks of SARS-CoV-2 Projected

THURSDAY, April 16, 2020 (HealthDay News) -- Recurrent winter outbreaks of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) are projected to occur after the initial pandemic wave, according to a study published online April 14 in Science.

Abstract/Full Text

Sharp Drop in Demand Seen for COVID-19 Tests at Private Labs

THURSDAY, April 16, 2020 (HealthDay News) -- There has been such a drop in demand for coronavirus disease 2019 (COVID-19) tests at private labs in the United States that they have "considerable" unused capacity and can test more patients with less severe symptoms, the American Clinical Laboratory Association (ACLA) says.

NBC News Article

CRISPR-Based Test Can Diagnose COVID-19 in Under 60 Minutes

THURSDAY, April 16, 2020 (HealthDay News) -- Researchers say they have developed a low-cost swab test that can diagnose coronavirus disease 2019 (COVID-19) infections in about 45 minutes.

Abstract/Full Text

FDA Urges COVID-19 Survivors to Donate Plasma

THURSDAY, April 16, 2020 (HealthDay News) -- The U.S. Food and Drug Administration is asking Americans who have recovered from coronavirus disease 2019 (COVID-19) to donate their blood plasma to help fight the pandemic.

More Information
American Red Cross

Novel Agent Promising for the Treatment of Schizophrenia

THURSDAY, April 16, 2020 (HealthDay News) -- For patients with an acute exacerbation of schizophrenia, SEP-363856, a non-D2-receptor-binding drug that has agonist activity at trace amine-associated receptor 1 (TAAR1) and 5-hydroxytryptamine type 1A receptors, reduces Positive and Negative Symptom Scale (PANSS) total score more than placebo, according to a study published in the April 16 issue of the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Quality Improvement Effort Cuts Blood Clots in Brain Injury Patients

THURSDAY, April 16, 2020 (HealthDay News) -- Implementation of an anticoagulation protocol reduces blood clots in patients with traumatic brain injury (TBI), according to a study published in the April 1 issue of The Joint Commission Journal on Quality and Patient Safety.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Post-Detox Treatment Lowers Mortality in Opioid Use Disorder

WEDNESDAY, April 15, 2020 (HealthDay News) -- People who receive additional treatment following medically managed opioid withdrawal have reduced mortality compared with those who do not receive treatment, according to a study recently published in Addiction.

Abstract/Full Text (subscription or payment may be required)

Survey Shows Lack of COVID-19 Concern Even Among Those at Risk

WEDNESDAY, April 15, 2020 (HealthDay News) -- Many individuals at greater risk for coronavirus disease 2019 (COVID-19) complications did not believe the virus would affect them at the beginning of Chicago's outbreak, according to a study published online April 9 in the Annals of Internal Medicine.

Abstract/Full Text

Obesity Is Risk Factor for COVID-19 Hospital Admission in <60s

WEDNESDAY, April 15, 2020 (HealthDay News) -- Obesity is associated with admission to the hospital for coronavirus disease 2019 (COVID-19) patients, according to a study published online April 9 in Clinical Infectious Diseases and a study not yet peer reviewed and posted on medRxiv.org.

Abstract/Full Text - Lighter (subscription or payment may be required)
Abstract/Full Text - Petrilli (subscription or payment may be required)

Prognostic Score Predicts Time to First Treatment in Leukemia

WEDNESDAY, April 15, 2020 (HealthDay News) -- An international prognostic score (IPS-E) can predict time to first treatment (TTFT) for chronic lymphocytic leukemia (CLL) patients with early, asymptomatic disease, according to a study published online April 8 in Blood.

Abstract/Full Text

SARS-CoV-2 Contamination of Air, Surfaces Examined in ICU, Wards

WEDNESDAY, April 15, 2020 (HealthDay News) -- Considerable severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) contamination of air and object surfaces is reported in intensive care units (ICUs) and general coronavirus disease 2019 (COVID-19) wards (GW), according to a study published online April 10 in Emerging Infectious Diseases, a publication of the U.S. Centers for Disease Control and Prevention.

Abstract/Full Text

Public Health Interventions Improved COVID-19 Control in Wuhan

WEDNESDAY, April 15, 2020 (HealthDay News) -- Multifaceted public health interventions improved control of the coronavirus disease 2019 (COVID-19) outbreak in Wuhan, China, according to a study published online April 10 in the Journal of the American Medical Association.

Abstract/Full Text
Editorial

Preoperative Metformin Tied to Better Surgical Outcomes

WEDNESDAY, April 15, 2020 (HealthDay News) -- Preoperative metformin prescriptions may be associated with decreased postoperative mortality and readmission among patients with diabetes undergoing a major surgical procedure, according to a study published online April 8 in JAMA Surgery.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Common Coronaviruses Are Highly Seasonal

WEDNESDAY, April 15, 2020 (HealthDay News) -- Common coronaviruses circulate seasonally, according to a study published online April 4 in the Journal of Infectious Diseases.

Abstract/Full Text (subscription or payment may be required)

CDC: Overall Prevalence of Self-Reported Hypertension 32.4 Percent

WEDNESDAY, April 15, 2020 (HealthDay News) -- The overall prevalence of self-reported hypertension is 32.4 percent, with prevalence higher among men than women and among blacks, according to research published in the April 10 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text

Review: Quarantine Effective for Reducing Infection, Death

TUESDAY, April 14, 2020 (HealthDay News) -- Quarantine is effective for reducing the number of people infected and deaths from coronavirus disease 2019 (COVID-19), according to a review published online April 8 in the Cochrane Database of Systematic Reviews.

Abstract/Full Text

U.S. Government Says COVID-19 Antibody Tests Must Be Free

TUESDAY, April 14, 2020 (HealthDay News) -- Health insurers and Medicaid must provide free coverage for tests to detect coronavirus 2019 (COVID-19) antibodies in people who have been infected, the federal government says.

CBS News Article
Johns Hopkins University

CDC: Public Policy Measures Important for Social Distancing

TUESDAY, April 14, 2020 (HealthDay News) -- Community mobility in four metropolitan areas decreased with the introduction of public policy measures supporting social distancing, which could help slow the spread of coronavirus disease 2019 (COVID-19), according to research published in the April 13 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text

First Saliva Test for COVID-19 Approved by FDA

TUESDAY, April 14, 2020 (HealthDay News) -- The first saliva test for coronavirus 2019 (COVID-19) was approved Monday by the U.S. Food and Drug Administration.

AP News Article
More Information

Medical Masks May Be Sufficient During COVID-19 Routine Care

TUESDAY, April 14, 2020 (HealthDay News) -- Use of medical masks, such as surgical or procedural masks, does not increase the risk for viral infection or respiratory illness, and their use may serve as a protective measure in instances of N95 respirator shortages, according to the results of a meta-analysis published online April 4 in Influenza and Other Respiratory Viruses.

Abstract/Full Text

First Wave of COVID-19 Abated With Control Measures in China

TUESDAY, April 14, 2020 (HealthDay News) -- Interventions implemented in China interrupted coronavirus disease 2019 (COVID-19) transmission in all areas outside of Hubei, and low transmissibility can be maintained by monitoring the instantaneous effective reproduction number (Rt), according to a study published online April 8 in The Lancet.

Abstract/Full Text
Editorial

Physicians Report Expanding Use of Off-Label COVID-19 Treatments

MONDAY, April 13, 2020 (HealthDay News) -- Hydroxychloroquine usage is expanding globally to treat coronavirus 2019 (COVID-19), although plasma from recovered patients is perceived as more effective than hydroxychloroquine, according to a report released by Sermo.

More Information

Chloroquine COVID-19 Trial Stopped After Patient Deaths

MONDAY, April 13, 2020 (HealthDay News) -- A study of chloroquine in coronavirus 2019 (COVID-19) patients was halted due to potentially deadly side effects.

The New York Times Article

COVID-19 Antibody Tests Underway in California

MONDAY, April 13, 2020 (HealthDay News) -- Large-scale studies of tests to check for antibodies to coronavirus 2019 (COVID-19) are underway in California. The findings from this research could help the United States develop strategies to get people back to work and restart the economy.

NBC News Article

Remdesivir May Improve Oxygen-Support Class in Severe COVID-19

MONDAY, April 13, 2020 (HealthDay News) -- Improvement in oxygen support status was observed in 68 percent of patients hospitalized with severe coronavirus disease 2019 (COVID-19) who received compassionate use of remdesivir, according to a study published online April 10 in the New England Journal of Medicine.

Abstract/Full Text

CDC Report Details Geographic Variation in U.S. COVID-19 Cases, Deaths

MONDAY, April 13, 2020 (HealthDay News) -- There is variation in the cumulative incidence of coronavirus disease 2019 (COVID-19) across jurisdictions in the United States, according to research published in the April 10 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text

Most Home BP Devices Available Online Are Not Validated

MONDAY, April 13, 2020 (HealthDay News) -- Most home blood pressure (BP) devices available online are nonvalidated, and they are sold at a lower cost than validated ones, according to a study published online April 13 in Hypertension.

Abstract/Full Text (subscription or payment may be required)

Physician's Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of April 6 to 10, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article

Neurologic Effects Seen in a Third of Hospitalized COVID-19 Patients

FRIDAY, April 10, 2020 (HealthDay News) -- Neurologic manifestations are common among hospitalized patients with COVID-19, according to a study published online April 10 in JAMA Neurology.

Abstract/Full Text
Editorial

FDA Approves New Way to Decontaminate N95 Face Masks

FRIDAY, April 10, 2020 (HealthDay News) -- The second emergency use authorization to decontaminate N95 face masks and equivalents for reuse by hospital health care workers has been issued by the U.S. Food and Drug Administration.

More Information

Temperature, UV Radiation Not Linked to Incidence of COVID-19

FRIDAY, April 10, 2020 (HealthDay News) -- Ambient temperature and ultraviolet (UV) radiation are not associated with the cumulative incidence rate or basic reproduction number (R0) of coronavirus disease 2019 (COVID-19), according to a research letter published online April 8 in the European Respiratory Journal.

Abstract/Full Text

Current Models for COVID-19 Diagnosis, Prognosis Unreliable

FRIDAY, April 10, 2020 (HealthDay News) -- Novel coronavirus (COVID-19)-related models that are published in the literature are poorly reported and at high risk for bias, raising concern that their predictions could be unreliable when applied in daily practice, according to a review published online April 7 in The BMJ.

Abstract/Full Text

Anxiety Up for Nonmedical Health Care Workers Versus Those on Front Lines

FRIDAY, April 10, 2020 (HealthDay News) -- Non-medically trained health care workers caring for patients with coronavirus disease 2019 (COVID-19) have an increased prevalence of anxiety compared with medically trained health care workers, according to a research letter published online April 6 in the Annals of Internal Medicine.

Abstract/Full Text

Face Masks Offer Slight Protective Effect From Flu-Like Illness

FRIDAY, April 10, 2020 (HealthDay News) -- Wearing face masks could be slightly protective against primary infection with influenza-like illness from casual community contact, according to a review that has not yet been peer reviewed and was posted online April 6 at medRxiv.org.

Abstract/Full Text

Incident Depression Increases With Body Mass Index

FRIDAY, April 10, 2020 (HealthDay News) -- The risk for incident depression increases with body mass index (BMI) among overweight and obese patients, according to a study published online April 8 in Obesity.

Abstract/Full Text (subscription or payment may be required)

Clinical Trial Underway to Test Nitric Oxide in COVID-19 Patients

THURSDAY, April 9, 2020 (HealthDay News) -- Doctors at the University of Alabama at Birmingham (UAB) are enrolling patients in an international clinical trial to find out if inhaled nitric oxide benefits those with novel coronavirus (COVID-19) who have severely damaged lungs.

More Information

NIH Launches Clinical Trial of Hydroxychloroquine for COVID-19

THURSDAY, April 9, 2020 (HealthDay News) -- A clinical trial to assess the antimalarial drug hydroxychloroquine as a treatment for adults with the novel coronavirus (COVID-19) is now underway, the U.S. National Institutes of Health said Thursday.

More Information

COVID-19 Came to New York City From Europe, Not Asia

THURSDAY, April 9, 2020 (HealthDay News) -- The novel coronavirus (COVID-19) has been circulating in New York City for longer than previously believed and most cases can be traced back to Europe, new research reveals.

More Information
Johns Hopkins University

FDA Warns of False Claims That Chlorine Dioxide Can Treat COVID-19

THURSDAY, April 9, 2020 (HealthDay News) -- A warning letter has been sent to a company marketing fraudulent and dangerous chlorine dioxide products for the prevention and treatment of the novel coronavirus (COVID-19), the U.S. Food and Drug Administration says.

More Information

Another COVID-19 Vaccine Trial Begins in the United States

THURSDAY, April 9, 2020 (HealthDay News) -- Another clinical trial of an experimental vaccine for the novel coronavirus 2019 (COVID-19) has been launched by U.S. researchers.

AP News Article

ATS Provides Interim Guidance for Management of COVID-19

THURSDAY, April 9, 2020 (HealthDay News) -- In a guidance document issued by the American Thoracic Society, interim recommendations are presented for management of coronavirus disease 2019 (COVID-19).

More Information

'Dead' Probiotic Treatment May Help Reduce Irritable Bowel Symptoms

THURSDAY, April 9, 2020 (HealthDay News) -- Probiotic treatment with dead bacteria is better than placebo at alleviating symptoms of irritable bowel syndrome (IBS), according to a study published online April 8 in The Lancet Gastroenterology & Hepatology.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Outcomes Better at One Year With Physical Therapy for Knee OA

THURSDAY, April 9, 2020 (HealthDay News) -- For patients with osteoarthritis of the knee, those undergoing physical therapy have less pain and functional disability at one year compared with those who receive an intraarticular glucocorticoid injection, according to a study published in the April 9 issue of the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Suppressing Stomach Acid May Up Intestinal Growth of MDROs

THURSDAY, April 9, 2020 (HealthDay News) -- Stomach acid suppression medications increase the odds of intestinal colonization with multidrug-resistant microorganisms (MDROs), according to a review and meta-analysis recently published in JAMA Internal Medicine.

Abstract/Full Text
Editorial (subscription or payment may be required)

COVID-19 Killing Two Times More Men Than Women in NYC

WEDNESDAY, April 8, 2020 (HealthDay News) -- The novel coronavirus (COVID-19) death rate in New York City is two times higher among men than among women, and men also have higher rates of infection and hospitalization, new data show.

The New York Times Article
More Information

CDC Removes Prescribing Guidelines for Antimalarial Drugs

WEDNESDAY, April 8, 2020 (HealthDay News) -- Guidelines for doctors on how to prescribe two antimalarial drugs that some believe may treat the novel coronavirus (COVID-19) are no longer available on the U.S. Centers for Disease Control and Prevention website.

CNN Article
More Information
Johns Hopkins University

Surgical, Cotton Masks Not Effective for Filtering SARS-CoV-2

WEDNESDAY, April 8, 2020 (HealthDay News) -- For patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), neither surgical nor cotton masks effectively filter SARS-CoV-2 during coughs, according to a research letter published online April 6 in the Annals of Internal Medicine.

Abstract/Full Text

Some Multidrug-Resistant Bacterial Infections Down in U.S.

WEDNESDAY, April 8, 2020 (HealthDay News) -- From 2012 to 2017, there were decreases in the incidence of some multidrug-resistant (MDR) bacterial infections in hospitalized patients in the United States, according to a study published in the April 2 issue of the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)

Side Effects Seen With Use of Chloroquine Against COVID-19

TUESDAY, April 7, 2020 (HealthDay News) -- The use of the antimalarial drug chloroquine to treat COVID-19 patients has been halted at several Swedish hospitals due to reported side effects such as cramps and loss of peripheral vision. Sahlgrenska University Hospital is one of those facilities. It stopped the use of chloroquine in the treatment of COVID-19 about two weeks ago.

Newsweek Article
Johns Hopkins University

Serious Concerns Associated With COVID-19 Pandemic Reported

TUESDAY, April 7, 2020 (HealthDay News) -- Serious concerns are associated with coronavirus disease 2019 (COVID-19), and many individuals are preparing by washing hands and self-isolating, according to a research letter published online April 7 in JAMA Internal Medicine.

Abstract/Full Text

Most COVID-19 Fatalities Are Men Over 50 With Chronic Disease

TUESDAY, April 7, 2020 (HealthDay News) -- Most fatal cases of coronavirus disease 2019 (COVID-19) occur in men aged older than 50 years with noncommunicable chronic diseases, according to a study published online April 3 in the American Journal of Respiratory and Critical Care Medicine.

Abstract/Full Text

No Treatment Change Needed for Peds IBD During COVID-19 Pandemic

TUESDAY, April 7, 2020 (HealthDay News) -- Preliminary data regarding outcomes for pediatric patients with inflammatory bowel disease (IBD) during the coronavirus disease 2019 (COVID-19) outbreak are reassuring, according to research published online March 31 in the Journal of Pediatric Gastroenterology and Nutrition.

Abstract/Full Text (subscription or payment may be required)

School Closures Could Further Complicate COVID-19 Effort

TUESDAY, April 7, 2020 (HealthDay News) -- Potential contagion prevention from school closures needs to be weighed against the potential loss of health care workers due to child care obligations during the coronavirus disease 2019 (COVID-19) pandemic, according to a study published online April 3 in The Lancet Public Health.

Abstract/Full Text

Radiotherapy for Prostate Cancer Adjusted During COVID-19

TUESDAY, April 7, 2020 (HealthDay News) -- In a special article published online April 1 in Advances in Radiation Oncology, a framework is laid out for the management of radiotherapy for prostate cancer patients during the coronavirus disease 2019 (COVID-19) pandemic.

Abstract/Full Text

Initial Invasive Strategy No Better in Stable Coronary Disease

MONDAY, April 6, 2020 (HealthDay News) -- For patients with stable coronary disease and moderate-to-severe ischemia, an initial invasive strategy does not improve outcomes, but it may improve angina-related health status, according to two studies published online March 30 in the New England Journal of Medicine.

Abstract/Full Text - Maron (subscription or payment may be required)
Abstract/Full Text - Spertus (subscription or payment may be required)
Editorial (subscription or payment may be required)

FDA Authorizes Use of Chinese-Approved Masks in United States

MONDAY, April 6, 2020 (HealthDay News) -- Emergency use authorization of protective masks that do not meet American standards has been announced by the U.S. Food and Drug Administration.

More Information: FDA
More Information: CDC
Johns Hopkins University

Majority of Physicians Report Serious Concerns About COVID-19

MONDAY, April 6, 2020 (HealthDay News) -- According to a national survey conducted by Harvard Medical School, the RAND Corporation, and Doximity, practicing physicians currently report substantial concerns about supplies, the government response, and availability of testing amid the COVID-19 pandemic.

More Information

Comorbidity, Age, Time to Treatment Linked to COVID-19 Progression

MONDAY, April 6, 2020 (HealthDay News) -- Factors associated with coronavirus disease 2019 (COVID-19) progression include comorbidity, age, and time from illness onset to antiviral treatment, according to a study published online March 27 in the Journal of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Hydroxychloroquine Can Shorten Time to Recovery in COVID-19

MONDAY, April 6, 2020 (HealthDay News) -- Hydroxychloroquine (HCQ) can shorten time to clinical recovery and promote pneumonia absorption among patients with coronavirus disease 2019 (COVID-19), according to a study that has not yet been peer reviewed and was posted online March 31 at medRxiv.org.

Abstract/Full Text (subscription or payment may be required)

Bacteremia Risk Higher in Older Patients Hospitalized With IBD

MONDAY, April 6, 2020 (HealthDay News) -- Older age is associated with an increased risk for bacteremia in hospitalized patients with inflammatory bowel disease (IBD), according to a study published in the March issue of the United European Gastroenterology Journal.

Abstract/Full Text

Model Shows Hep C-Infected Kidney Transplants Beneficial, Cost-Effective

MONDAY, April 6, 2020 (HealthDay News) -- Transplanting hepatitis C virus (HCV)-infected kidneys into uninfected recipients and then treating patients with antiviral therapy leads to a higher quality of life and is less costly than waiting for transplantation with an uninfected kidney, according to a study recently published in the American Journal of Kidney Diseases.

Abstract/Full Text (subscription or payment may be required)

Physician's Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of March 30 to April 3, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article
Read Full Article

Enrollment Begins in NIH-Sponsored Trial of Remdesivir for COVID-19 Patients

FRIDAY, April 3, 2020 (HealthDay News) -- A number of institutions this week announced their participation in an international clinical drug trial evaluating the safety and efficacy of remdesivir in hospitalized patients with the novel coronavirus 2019 (COVID-19).

More Information - Northwestern
More Information - Cedars Sinai
More Information - UC Davis
More Information - Roswell Park
More Information - University of Illinois at Chicago

Test Vaccine Elicits Strong Ab Response to SARS-CoV-2 in Mice

FRIDAY, April 3, 2020 (HealthDay News) -- Microneedle array (MNA) delivery of trimeric coronavirus spike (S) protein subunit vaccines seems promising for immunization against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, according to research published online April 2 in EBioMedicine.

Abstract/Full Text

Model Projects COVID-19 Deaths in Italy Through Mid-April

FRIDAY, April 3, 2020 (HealthDay News) -- Modeling suggests that in Italy, the number of coronavirus disease 2019 (COVID-19) intensive care unit (ICU) patients will continue increasing into April, according to a report published April 1 by the European Society of Anaesthesiology.

More Information

Rivaroxaban Prevents VTE After Lower-Limb Surgery

FRIDAY, April 3, 2020 (HealthDay News) -- Following nonmajor orthopedic surgery of the lower limb, rivaroxaban is superior to enoxaparin for prevention of major venous thromboembolism, according to a study published online March 29 in the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)

Early Deep Remission of Crohn Disease Tied to Better Outcomes

FRIDAY, April 3, 2020 (HealthDay News) -- Deep early remission of Crohn disease is associated with a significant decrease in long-term adverse effects, according to a study published online March 26 in Gastroenterology.

Abstract/Full Text (subscription or payment may be required)

Many Legal Marijuana Products Too Strong for Treating Pain

FRIDAY, April 3, 2020 (HealthDay News) -- Legally dispensed marijuana products have stronger concentrations of tetrahydrocannabinol (THC) and cannabidiol (CBD) than needed for chronic pain relief, according to a study published online March 26 in PLOS ONE.

Abstract/Full Text

Unemployed Workers Less Likely to Be Uninsured Post-ACA

THURSDAY, April 2, 2020 (HealthDay News) -- Following implementation of the Affordable Care Act (ACA), unemployed workers were less likely to be uninsured, and uninsurance rates decreased more in states with Medicaid expansion, according to a report from the Urban Institute and the Robert Wood Johnson Foundation.

More Information

Proton Pump Inhibitor Therapy May Up Fracture Risk in Children

THURSDAY, April 2, 2020 (HealthDay News) -- Proton pump inhibitors (PPIs) taken for acid reflux may lead to an increased risk for fractures in children and adolescents, according to a study published online March 12 in the Journal of Pediatric Gastroenterology and Nutrition.

Abstract/Full Text (subscription or payment may be required)

FDA Pulls Heartburn Drug Zantac From Market

WEDNESDAY, April 1, 2020 (HealthDay News) -- All versions of the heartburn drug Zantac (ranitidine) have been pulled from the U.S. market due to possible contamination with a probable human carcinogen, the U.S. Food and Drug Administration said Wednesday.

More Information

Imported Masks, Other Medical Supplies Arriving in U.S.

WEDNESDAY, April 1, 2020 (HealthDay News) -- For the first time since February, imported N95 medical masks are arriving in the United States, but they are not nearly enough to meet demand as COVID-19 cases climb.

AP News Article
More Information

U.S. Coronavirus Death Toll Could Reach 240,000, Task Force Warns

WEDNESDAY, April 1, 2020 (HealthDay News) -- The White House coronavirus task force delivered a tough statistic to Americans late Tuesday, warning that the U.S. death toll from COVID-19 could climb to 240,000, even with social distancing policies in place.

CBS News Article
Johns Hopkins University
More Information

ENDO: Liraglutide May Benefit Adolescents With Obesity

WEDNESDAY, April 1, 2020 (HealthDay News) -- Liraglutide plus lifestyle therapy results in a significantly greater reduction in body mass index (BMI) standard-deviation score than placebo among adolescents with obesity, according to a study published online March 31 in the New England Journal of Medicine to coincide with the virtual meeting of The Endocrine Society, held from March 28 to 31.

Abstract/Full Text (subscription or payment may be required)
More Information

Low Vitamin D May Reduce Mobility After Hip Fracture Surgery

WEDNESDAY, April 1, 2020 (HealthDay News) -- Vitamin D deficiencies are associated with a lower likelihood of older patients regaining independent walking ability following hip fracture surgery, according to a study recently published in the American Journal of Clinical Nutrition.

Abstract/Full Text (subscription or payment may be required)

Polypharmacy Ups Postchemo Hospitalization Risk in Seniors

WEDNESDAY, April 1, 2020 (HealthDay News) -- Older patients taking five or more medications in the six months before intravenous (IV) chemotherapy are at higher risk for postchemotherapy inpatient hospitalizations, according to a study published online March 18 in the Journal of Geriatric Oncology.

Abstract/Full Text

Last Updated: