February 2019 Briefing - Rheumatology

Here are what the editors at HealthDay consider to be the most important developments in Rheumatology for February 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

FDA: Pulmonary Embolism Risk Up With Tofacitinib 10 mg for RA

THURSDAY, Feb. 28, 2019 (HealthDay News) -- A safety clinical trial has revealed that tofacitinib (Xeljanz, Xeljanz XR) 10 mg twice daily is associated with an increased risk for pulmonary embolism (PE) and death among patients with rheumatoid arthritis (RA), the U.S. Food and Drug Administration warned in a safety alert this week.

More Information

Sustained Smoking Cessation May Delay, Prevent Seropositive RA

WEDNESDAY, Feb. 27, 2019 (HealthDay News) -- While smoking is a strong risk factor for seropositive rheumatoid arthritis (RA), sustained smoking cessation could delay or even prevent disease development, according to a study published online Feb. 21 in Arthritis Care & Research.

Abstract/Full Text (subscription or payment may be required)

Ultrasound of Calcaneus Efficient for Screening Bone Health

TUESDAY, Feb. 26, 2019 (HealthDay News) -- Ultrasonography (US) of the calcaneus is efficient for screening bone health, according to a study published in the March issue of the Journal of the American Osteopathic Association.

Abstract/Full Text

2014 to 2017 Saw Improvement in Burnout for U.S. Physicians

MONDAY, Feb. 25, 2019 (HealthDay News) -- From 2014 to 2017, there was an improvement in burnout and satisfaction with work-life integration among U.S. physicians, according to a study published online Feb. 22 in the Mayo Clinic Proceedings.

Abstract/Full Text

FDA: Gout Drug Uloric Increases Risk of Death

FRIDAY, Feb. 22, 2019 (HealthDay News) -- The gout medicine Uloric (febuxostat) carries a higher risk of death than allopurinol, according to the U.S. Food and Drug Administration.

More Information

National Health Spending Set to Increase 5.5 Percent Annually

FRIDAY, Feb. 22, 2019 (HealthDay News) -- National health spending is projected to increase at an annual rate of 5.5. percent from 2018 to 2027, with fundamental economic and demographic factors the main drivers, according to a report published online Feb. 20 in Health Affairs.

Abstract/Full Text (subscription or payment may be required)

Most Patients Do Not Disclose Complementary Medicine Use

FRIDAY, Feb. 22, 2019 (HealthDay News) -- Just one-third of users of biologically based complementary medicine (CM) disclose their use to traditional health care providers, according to a review published online Feb. 7 in Scientific Reports.

Abstract/Full Text

Guideline Covers Extracutaneous Manifestations of Psoriasis

FRIDAY, Feb. 22, 2019 (HealthDay News) -- The extracutaneous manifestations of psoriasis and guidance on use of biologic treatment for management of psoriasis are discussed in two new guidelines published online Feb. 13 in the Journal of the American Academy of Dermatology.

Abstract/Full Text - Elmets
Abstract/Full Text - Menter

Vertical Integration Has Little Impact on Quality Measures

THURSDAY, Feb. 21, 2019 (HealthDay News) -- Vertical integration between hospitals and physicians has little impact on quality measures, while increased hospital market concentration is strongly associated with reduced quality in measures of patient satisfaction, according to a study published online Feb. 9 in Medical Care Research and Review.

Abstract/Full Text

New Kaiser Permanente Medical School Plans to Waive Tuition

WEDNESDAY, Feb. 20, 2019 (HealthDay News) -- A new medical school to be opened by California-based health system Kaiser Permanente will waive tuition for all students in its first five graduating classes.

The New York Times Article
More Information

Altered Gut Microbiome Seen in Patients With Active Lupus

WEDNESDAY, Feb. 20, 2019 (HealthDay News) -- The microbiome of patients with systemic lupus erythematosus (SLE), particularly those with increased disease activity, has reduced taxonomic complexity, according to a study published online Feb. 19 in the Annals of the Rheumatic Diseases.

Abstract/Full Text

Hospital Prices Growing Faster Than Physician Prices

FRIDAY, Feb. 15, 2019 (HealthDay News) -- Growth in hospital prices and payments outpaced growth in physician prices and payments from 2007 through 2014, according to a report published in the February issue of Health Affairs.

Abstract/Full Text (subscription or payment may be required)

Fewer Older Men Assessed, Treated for Osteoporosis

FRIDAY, Feb. 15, 2019 (HealthDay News) -- Fewer older men than women undergo evaluation for or management of osteoporosis, according to a study published online Feb. 12 in the Journal of Investigative Medicine.

Abstract/Full Text

Hip Preservation Appropriateness Guidelines May Be Limited

THURSDAY, Feb. 14, 2019 (HealthDay News) -- The American Academy of Orthopaedic Surgeons (AAOS) hip preservation surgery appropriateness classification system is driven almost entirely by age and radiographic hip osteoarthritis (OA) evaluation, according to a study published online Jan. 24 in Arthritis Care & Research.

Abstract/Full Text (subscription or payment may be required)

Physical Activity Down Across Chronic Disease Subgroups

THURSDAY, Feb. 14, 2019 (HealthDay News) -- People with a wide variety of chronic diseases are less physically active than individuals without chronic diseases, according to a study published online Feb. 5 in the International Journal of Epidemiology.

Abstract/Full Text

Yoga May Help With Rheumatoid Arthritis Symptoms, Severity

WEDNESDAY, Feb. 13, 2019 (HealthDay News) -- Yoga may be effective as a complementary or adjunct therapy for patients with rheumatoid arthritis (RA) taking disease-modifying antirheumatic drugs (DMARDs), according to a study published online Feb. 1 in Restorative Neurology and Neuroscience.

Abstract/Full Text (subscription or payment may be required)

Health Care Spending Per Person Increased to $5,641 in 2017

TUESDAY, Feb. 12, 2019 (HealthDay News) -- In 2017, health care spending per person reached $5,641, according to the Health Care Cost Institute (HCCI) annual Health Care Cost and Utilization Report.

Health Care Cost and Utilization Report

Many Systematic Reviews Do Not Fully Report Adverse Events

TUESDAY, Feb. 12, 2019 (HealthDay News) -- Many systematic review protocols in the International Prospective Register of Systematic Reviews (PROSPERO) do not include adverse event reporting, according to a study published in the April issue of the Journal of Clinical Epidemiology.

Abstract/Full Text

Low Fitness, Obesity Linked to Later Disability Pension

MONDAY, Feb. 11, 2019 (HealthDay News) -- Among men, low cardiorespiratory fitness and obesity in adolescence are associated with an increased risk for later receipt of a disability pension, according to a study published online Feb. 12 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Johnson & Johnson to Provide Drug Prices in TV Ads

FRIDAY, Feb. 8, 2019 (HealthDay News) -- In a drug industry first, Johnson & Johnson will start giving the list prices of its prescription drugs in television ads.

AP News Article

Discord Found in Clinician-, Criteria-Based Fibromyalgia Diagnosis

THURSDAY, Feb. 7, 2019 (HealthDay News) -- There is disagreement between clinical diagnosis and criteria-based diagnosis of fibromyalgia, according to a study published online Feb. 6 in Arthritis Care & Research.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

MRI-Guided Tx Strategy Not Superior for Rheumatoid Arthritis

WEDNESDAY, Feb. 6, 2019 (HealthDay News) -- A magnetic resonance imaging (MRI)-guided treat-to-target strategy is not associated with improved disease activity remission rates for patients with rheumatoid arthritis (RA) in clinical remission, according to a study published in the Feb. 5 issue of the Journal of the American Medical Association.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Compounded Topical Pain Creams No Better Than Placebo

TUESDAY, Feb. 5, 2019 (HealthDay News) -- Compounded topical pain creams are no better than placebo creams for neuropathic pain, nociceptive pain, or mixed pain, according to a study published online Feb. 5 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Long-Term Opioid Use With OA Varies Across States

TUESDAY, Feb. 5, 2019 (HealthDay News) -- There is substantial variation across states in rates of long-term opioid therapy among patients with advanced osteoarthritis, according to a study published online Jan. 28 in Arthritis & Rheumatology.

Abstract/Full Text (subscription or payment may be required)

Tofacitinib Benefits Sustained for Two Years in Patients With RA

MONDAY, Feb. 4, 2019 (HealthDay News) -- The clinical benefits of tofacitinib in combination with methotrexate are sustained over two years among patients with rheumatoid arthritis (RA), according to a study published online Jan. 22 in Arthritis & Rheumatology.

Abstract/Full Text (subscription or payment may be required)

Discontinuing TNFi Before Gestational Week 20 Is Feasible

FRIDAY, Feb. 1, 2019 (HealthDay News) -- Discontinuing tumor necrosis factor inhibitors (TNFi) before gestational week 20 in women with well-controlled rheumatoid arthritis (RA) or juvenile idiopathic arthritis (JIA) is not associated with disease worsening in late pregnancy, according to a study published online Jan. 21 in Arthritis & Rheumatology.

Abstract/Full Text (subscription or payment may be required)

Pharmacist-Led Phone Follow-Up May Cut Readmission Rates

FRIDAY, Feb. 1, 2019 (HealthDay News) -- A pharmacist-led, postdischarge structured telephone follow-up (TFU) intervention can reduce 30-day and 90-day readmission rates for polypharmacy patients, according to a study published online Jan. 23 in the British Journal of Clinical Pharmacology.

Abstract/Full Text

Longitudinal TNF Levels Mainly Stable With Adalimumab in RA

FRIDAY, Feb. 1, 2019 (HealthDay News) -- For patients with rheumatoid arthritis (RA), longitudinal tumor necrosis factor (TNF) concentrations are mainly stable during adalimumab treatment, although early low TNF is strongly linked to nonresponse to treatment, according to a study published in the Jan. 30 issue of Science Translational Medicine.

Abstract/Full Text

Last Updated: