July 2019 Briefing - Rheumatology

Here are what the editors at HealthDay consider to be the most important developments in Rheumatology for July 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Burnout Symptoms May Up Racial Bias Among Resident Physicians

WEDNESDAY, July 31, 2019 (HealthDay News) -- Symptoms of burnout seem to be associated with greater explicit and implicit racial bias among resident physicians, according to a study published online July 26 in JAMA Network Open.

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$70 Million Settlement Reached in Generic Drug Delay Case

TUESDAY, July 30, 2019 (HealthDay News) -- Three drug companies will pay a total of nearly $70 million to California to settle charges of delaying the sale of generic drugs to keep brand-name drug prices high, the state's attorney general said Monday.

AP News Article

National Norms Developed for Assessing Medical School Empathy

TUESDAY, July 30, 2019 (HealthDay News) -- National norms have been developed for assessing empathy among men and women at different levels of medical school education, according to a study published in the August issue of the Journal of the American Osteopathic Association.

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Minor Changes in BMD Seen With Tenofovir PrEP in Short Term

THURSDAY, July 25, 2019 (HealthDay News) -- Tenofovir preexposure prophylaxis (PrEP) therapy does not appear to be associated with clinically significant declines in bone mineral density (BMD) in the short term, according to a study published online June 19 in AIDS Research and Human Retroviruses.

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Cancer Risks Examined in Rheumatoid Arthritis Patients

WEDNESDAY, July 24, 2019 (HealthDay News) -- Compared with the general population, there is an increased risk for certain cancers in patients with rheumatoid arthritis (RA) in Singapore, according to a study published online July 11 in the International Journal of Rheumatic Diseases.

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Filgotinib Bests Placebo in Tx of Refractory Rheumatoid Arthritis

TUESDAY, July 23, 2019 (HealthDay News) -- Among patients with moderately to severely active rheumatoid arthritis (RA) resistant to previous therapy with biologic agents, a significantly higher clinical response rate was seen at 12 weeks for those receiving filgotinib versus placebo, according to a study published in the July 23/30 issue of the Journal of the American Medical Association.

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Initial Sustained Remission Common in Rheumatoid Arthritis

MONDAY, July 22, 2019 (HealthDay News) -- Six-month sustained remission (SR) is not uncommon in patients with rheumatoid arthritis (RA), according to research published online July 12 in the International Journal of Rheumatic Diseases.

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FRAX Score Underestimates Risk for Fracture in Multiple Sclerosis

FRIDAY, July 19, 2019 (HealthDay News) -- Multiple sclerosis (MS) is a risk factor for major fractures independent of the Fracture Risk Assessment tool (FRAX) score, according to a study published in the June issue of the Journal of Bone and Mineral Research.

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Safety Practice Violations ID'd in Septic Arthritis Outbreak

THURSDAY, July 18, 2019 (HealthDay News) -- Breaches of recommended infection prevention practices have been identified in an outbreak of septic arthritis cases after intra-articular injections performed in a private outpatient facility, according to a report published online July 17 in Infection Control & Hospital Epidemiology.

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About One in 20 Patients Exposed to Preventable Harm

THURSDAY, July 18, 2019 (HealthDay News) -- The pooled prevalence of preventable patient harm is 6 percent across a range of medical settings globally, according to a review published online July 17 in The BMJ.

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Opioids Commonly Prescribed in Emergency Department for Gout

MONDAY, July 15, 2019 (HealthDay News) -- More than one-fourth of patients with acute gout discharged from the emergency department receive an opioid prescription, according to a study published online July 2 in Arthritis Care & Research.

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Tool Uses Spine X-Rays to Assess Response to Osteoporosis Tx

MONDAY, July 15, 2019 (HealthDay News) -- A new measure derived from conventional X-rays and a machine learning algorithm is effective for assessing bone-specific effects of osteoporosis treatment, according to a pilot study published in the July issue of Skeletal Radiology.

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Serious Misdiagnosis-Related Harms Mostly Due to 'Big Three'

FRIDAY, July 12, 2019 (HealthDay News) -- Vascular events, infections, and cancers account for about three-quarters of serious misdiagnosis-related harms, according to a study published online July 11 in Diagnosis.

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Medicare Drug Rebate Plan Withdrawn by Trump Administration

THURSDAY, July 11, 2019 (HealthDay News) -- A plan to let Medicare patients receive rebates that drug companies currently pay to insurers and middlemen has been withdrawn by the Trump administration.

AP News Article

Capping Work Hours in Residency Does Not Impact Outcomes Later

THURSDAY, July 11, 2019 (HealthDay News) -- Exposure of U.S. physicians to work-hour reforms during residency training is not associated with post-training differences in patient mortality, readmissions, or costs of care, according to a study published online July 11 in The BMJ.

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Elderly-Onset Rheumatoid Arthritis Ups Bone Erosion Risk

THURSDAY, July 11, 2019 (HealthDay News) -- Elderly-onset rheumatoid arthritis (EORA) is a risk factor for bone erosions, even with clinical disease remission, according to a study published in the June issue of the International Journal of Rheumatic Diseases.

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Health Care Professionals Exhibit Gender Bias

THURSDAY, July 11, 2019 (HealthDay News) -- Survey results show that health care professionals have implicit and explicit gender bias, according to a study published online July 5 in JAMA Network Open.

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EHR System-Generated In-Basket Messages Linked to Burnout

TUESDAY, July 9, 2019 (HealthDay News) -- Receipt of more than the average number of electronic health record (EHR) system-generated in-basket messages is associated with an increased probability of physician burnout, according to a study published in the July 1 issue of Health Affairs.

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Rule Requiring Drug Prices in TV Ads Blocked by Judge

TUESDAY, July 9, 2019 (HealthDay News) -- A Trump administration rule to force pharmaceutical companies to disclose the list prices of their drugs in television ads was blocked Monday by a federal judge.

The New York Times Article

In-Hospital Maternal Mortality Down in Pregnancies With Lupus

TUESDAY, July 9, 2019 (HealthDay News) -- In-hospital maternal mortality decreased from 1998 to 2015 in systemic lupus erythematosus (SLE) and non-SLE pregnancies, with a greater decline for SLE pregnancies, according to a study published online July 9 in the Annals of Internal Medicine.

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Adults With Cerebral Palsy at Higher Risk for Osteoporosis

TUESDAY, July 9, 2019 (HealthDay News) -- Cerebral palsy (CP) is associated with an increased risk for osteoporosis and osteoarthritis, according to a study published in the August issue of Bone.

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Tanezumab Improves Scores for Pain, Function in Osteoarthritis

WEDNESDAY, July 3, 2019 (HealthDay News) -- For patients with osteoarthritis (OA) of the knee or hip, tanezumab is associated with significant improvements in pain and physical function versus placebo, according to a study published in the July 2 issue of the Journal of the American Medical Association.

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Considerable Number of Patients Receive Surprise Hospital Charges

TUESDAY, July 2, 2019 (HealthDay News) -- Eighteen percent of all emergency department visits and 16 percent of in-network hospital stays have at least one out-of-network charge, according to a report published June 20 by the Kaiser Family Foundation.

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Romosozumab Increases Bone Formation, Cuts Bone Resorption

MONDAY, July 1, 2019 (HealthDay News) -- For postmenopausal women with osteoporosis, romosozumab increases bone formation and decreases bone resorption, according to a study published online June 24 in the Journal of Bone and Mineral Research.

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